Does Autofluorescence Imaging Videoendoscopy System Improve the Colonoscopic Polyp Detection Rate?-A Pilot Study

Matsuda, Takahisa; Saito, Yutaka; Fu, Kuang‐I; Uraoka, Toshio; Kobayashi, Nozomu; Nakajima, Takeshi; Ikehara, Hisatomo; Mashimo, Yumi; Shimoda, Tadakazu; Murakami, Yoshitaka; Parra‐Blanco, Adolfo; Fujimori, Takahiro; Saito, Daizo

doi:10.1111/j.1572-0241.2008.01931.x

Cited by 119 publications

(101 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Quantitative determination of the AF intensity was also helpful in the distinction between adenomas and hyperplastic polyps, which is in agreement with previous reports (11)(12)(13)(14)(15). McCallum et al have reported that using a different index of AF intensity (AF intensity ratio) allowed colorectal adenomas to be distinguished from hyperplastic polyps with a sensitivity of 85% and specificity of 81% (14).…”

Section: Discussionsupporting

confidence: 90%

“…Recently, several groups have reported on the usefulness of AF endoscopy in the differential diagnosis of colorectal mucosal lesions, suggesting that AF endoscopy is useful for distinguishing adenomas from hyperplastic polyps (11)(12)(13)(14)(15). However, little is known about the role of AF endoscopy in the diagnosis of colorectal carcinomas.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Quantitative analysis of colorectal mucosal lesions by autofluorescence endoscopy: Discrimination of carcinomas from other lesions

Arita

Mitsuyama

Kawano³

et al. 2011

Oncol Rep

View full text Add to dashboard Cite

Abstract.A newly developed autofluorescence (AF) imaging technique was applied during colonoscopy in a clinical setting. This pilot study was conducted to evaluate the clinical feasibility of applying AF endoscopy for distinguishing colorectal lesions. A total of 54 colorectal mucosal lesions obtained from 43 patients who underwent both white-light and AF endoscopy and were treated by endoscopy or surgery were assessed. Of the lesions, 11 were hyperplastic polyps, 30 were adenomas and 13 were carcinomas. To quantify the AF intensity, a color-contrast index (CCI) was determined and evaluated in relation to the histology, size and shape of each lesion. CCI was significantly associated with the histology and size of the lesions, but not their shape. CCI increased as the malignant potential increased (in the order of hyperplastic polyps → adenomas → carcinomas), irrespective of the lesion size (r=0.797, p<0.0001 for size >8 mm; r=0.622, p=0.0045 for size >8 mm but >15 mm; r=0.644, p=0.0071 for size >15 mm). In each size group, CCI tended to be higher for carcinomas than for adenomas, and also higher for adenomas than for hyperplastic polyps. CCI allowed discrimination of adenomas/carcinomas from hyperplastic polyps with 95.3% sensitivity and 63.6% specificity (cut-off value, 14.5), and of colorectal carcinomas from adenomas with 84.6% sensitivity and 80.0% specificity (cut-off value, 28.0). These results suggest that the quantitative analysis of AF intensity using CCI is helpful to discriminate among different types of colorectal mucosal lesions, including carcinomas.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Quantitative analysis of colorectal mucosal lesions by autofluorescence endoscopy: Discrimination of carcinomas from other lesions

Arita

Mitsuyama

Kawano³

et al. 2011

Oncol Rep

View full text Add to dashboard Cite

show abstract

“…Some studies have proposed the efficacy of AFI for detecting colorectal neoplasms [10,[20][21][22]. Matsuda et al reported a study in which a single experienced endoscopist conducted back-to-back colonoscopies of the right-sided colon using AFI and WLE.…”

Section: Detectionmentioning

confidence: 99%

“…AFI and WLE detected 100 and 73 polyps, respectively. The miss rate for all polyps with AFI (30 %) was significantly lower than that with WLE (49 %) (P = 0.01) [10]. We compared the rates at which experienced and less-experienced endoscopists detected adenomas using AFI and conventional high-resolution endoscopy (HRE).…”

Section: Detectionmentioning

confidence: 99%

“…In this aspect, the diagnostic ability of NBI is closely associated with the ability to recognize vascular patterns, thus the diagnostic accuracy of NBI appears to be dependent on the experience of individual endoscopists. AFI is another novel IEE technology that can capture fluorescence (500-630 nm) emitted from the fluorophores in human tissue [9,10]. AFI can assess lesions without any morphological assessments based on the fluorescence intensity.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The efficacy of autofluorescence imaging in the diagnosis of colorectal diseases

Moriichi

Fujiya

Okumura

2016

Clin J Gastroenterol

View full text Add to dashboard Cite

Image-enhanced endoscopy (IEE) has been developed and is applied in the clinical setting throughout the world. Most reports regarding IEE have evaluated the efficacy of narrow-band imaging (NBI) in the diagnosis of gastrointestinal disorders. Although autofluorescence imaging (AFI) is a form of IEE, its usefulness remains unclear. The present review focused on the efficacy of AFI in the diagnosis of colorectal disease, particularly neoplasia and ulcerative colitis (UC). AFI-based diagnoses are made via the subjective judgment of the color on the monitor. The efficacy of AFI in detection and differentiation in patients with colorectal neoplastic lesions remains controversial, which may be dependent on the study design and the diagnostic procedures. Although the number of the reports related to UC is very small, most suggest that AFI is effective in UC patients. AFI is distinct from other modalities in that it can quantitatively assess the lesion based on the fluorescence intensity without any morphological assessments. AFI could be useful for patients with colorectal disease.Keywords Autofluorescence imaging (AFI) Á Colorectal neoplasia Á Ulcerative colitis (UC) Á Colitis-associated cancer Á Narrow-band imaging (NBI) Á Image-enhanced endoscopy (IEE) Á White light endoscopy (WLE)

show abstract

Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum

Brown

Baraza²

2010

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

show abstract

Does Autofluorescence Imaging Videoendoscopy System Improve the Colonoscopic Polyp Detection Rate?-A Pilot Study

Abstract: AFI detects more polyps in the right-sided colon compared to WL colonoscopy.

Cited by 119 publications

References 37 publications

Quantitative analysis of colorectal mucosal lesions by autofluorescence endoscopy: Discrimination of carcinomas from other lesions

Quantitative analysis of colorectal mucosal lesions by autofluorescence endoscopy: Discrimination of carcinomas from other lesions

The efficacy of autofluorescence imaging in the diagnosis of colorectal diseases

Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum

Contact Info

Product

Resources

About