Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum

Abstract

There appears to be strong evidence that chromoscopy enhances the detection of neoplasia in the colon and rectum. Patients with neoplastic polyps, particularly those with multiple polyps, are at increased risk of developing colorectal cancer. Such lesions, which presumably would be missed with conventional colonoscopy, could contribute to the interval cancer numbers on any surveillance programme.

Prospective, randomized, back-to-back trial evaluating the usefulness of i-SCAN in screening colonoscopy

“…Patients with neoplastic polyps, particularly those with multiple polyps, are at an increased risk of developing colorectal cancer. 1 Because chromoendoscopy is impractical during routine practice, several alternative approaches have been introduced to enhance the contrast of the mucosal surface without the use of dye. Of the different image-enhancing techniques, NBI has been the most extensively studied for adenoma detection.…”

Can we improve adenoma detection rates? A systematic review of intervention studies

“…These include higher definition colonoscopes to enhance resolution, 63 chromoendoscopy with dyes to highlight abnormal areas, 64,65 and proprietary technologies that electronically mimic chromoendoscopy (eg, narrow-band imaging, 66 Fujinon Intelligent Color Enhancement [FICE], 67 and the Pentax system's I-Scan 68 ). Optimization of adenoma detection may ultimately involve both improved technology and enhancement of the endoscopist's performance.…”

Expert opinions and scientific evidence for colonoscopy key performance indicators

“…This so-called Detect InSpect Characterise Resect And Discard (DISCARD) strategy—mainly for polyps ≤5 mm—has been summarised in multiple reviews and meta-analyses,237–241 and in a recent ASGE recommendation update 242. This review shows that almost all endoscopic techniques seem to reach high accuracy rates in endoscopic polyp differential diagnosis, mainly based on studies from expert centres 86…”