2021
DOI: 10.36660/abc.20190758
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Doença de Kawasaki: Preditores de Resistência à Imunoglobulina Intravenosa e Complicações Cardíacas

Abstract: Fundamento: A doença de Kawasaki (DK) é a principal causa de cardiopatia adquirida em idade pediátrica nos países desenvolvidos. Objetivos: Identificar fatores preditores de resistência à imunoglobulina intravenosa (IGIV), calcular a eficácia dos modelos preditores japoneses e caracterizar as complicações cardíacas. Métodos: Análise retrospectiva dos casos de DK entre janeiro de 2006 e julho de 2018 em um hospital pediátrico português. Foram construídas curvas ROC para encontrar fatores preditores de resistênc… Show more

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Cited by 11 publications
(13 citation statements)
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“…The three models of risk scores developed, namely Kobaysahi et al, 7 Sano et al 8 and Egami et al, 9 validated for the Japanese population, [7][8][9] do not work properly in western, ethnically mixed and Chinese populations. [10][11][12][13][14] A similar situation was observed by Faim et al, 3 where the respective models validated in Japan did not perform well either. 3 It is worth noting that in the study by Faim et al about 25% of the patients had coronary involvement, 40% of them had aneurysm formation, in addition to other cardiovascular complications.…”
supporting
confidence: 78%
See 3 more Smart Citations
“…The three models of risk scores developed, namely Kobaysahi et al, 7 Sano et al 8 and Egami et al, 9 validated for the Japanese population, [7][8][9] do not work properly in western, ethnically mixed and Chinese populations. [10][11][12][13][14] A similar situation was observed by Faim et al, 3 where the respective models validated in Japan did not perform well either. 3 It is worth noting that in the study by Faim et al about 25% of the patients had coronary involvement, 40% of them had aneurysm formation, in addition to other cardiovascular complications.…”
supporting
confidence: 78%
“…[10][11][12][13][14] A similar situation was observed by Faim et al, 3 where the respective models validated in Japan did not perform well either. 3 It is worth noting that in the study by Faim et al about 25% of the patients had coronary involvement, 40% of them had aneurysm formation, in addition to other cardiovascular complications. CAA and other cardiovascular complications in the acute phase, including myocarditis, cardiogenic shock and pericardial effusion, are described in the literature.…”
supporting
confidence: 78%
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“…Reconhece-se, entretanto, a DK como um problema de saúde pública nos países desenvolvidos, não sendo dada a devida importância nos países subdesenvolvidos. 27,28 Denotam-se, de maneira geral, a incipiência de estudos e a necessidade de fomento de mais pesquisas acerca da temática.…”
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