Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort

Abstract

Comorbidities showed clinically relevant associations with disease burden. Therefore, the role of comorbidities in hand OA should be considered when interpreting disease outcomes and in patient management.

Illness perceptions and their association with 2 year functional status and change in patients with hand osteoarthritis

“…The present study is part of the Hand OSTeoArthritis in Secondary care (HOSTAS) study, an ongoing observational cohort study in hand OA 26 . For this report, patients included from January 2011 onwards and who completed relevant questionnaires were considered.…”

“…Patients with secondary hand OA (e.g., due to trauma) and patients with hand symptoms explained by another diagnosis were excluded 26 . Patients were followed annually with postal questionnaires and biennially with an additional research visit.…”

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management

“…[H2] Novel imaging methods in development differentiation between the soft tissues in the hand and fast processing times 108 . To date, these techniques have been predominantly used for in vitro and ex vivo applications, whereas their use in vivo, particularly in patients with hand OA, is limited and is still undergoing development and testing 109 . The use of systemic contrast agents for some of these applications might limit their use and acceptability to patients.…”

In thumb base osteoarthritis structural damage is more strongly associated with pain than synovitis

“…All participants gave written informed consent. Details on recruitment and selection of the three cohorts have been published elsewhere 15,20,21 .…”