Diversity and emergence of multi-resistant Staphylococcus spp. isolated from subclinical mastitis in cows in of the state of Piauí, Brazil

Oliveira, Raylson Pereira de; Silva, José Givanildo da; Aragão, Breno Bezerra; Carvalho, Rafaella Grenfell de; Juliano, María A.; Frazzon, Jeverson; Farias, Márcia Paula Oliveira; Mota, Rinaldo Aparecido

doi:10.1007/s42770-022-00822-1

Cited by 5 publications

(2 citation statements)

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“…It is isolated from fermented foods, and has been also been isolated among animals, e.g. in dogs, cats, goats, horses, monkeys, pigs, rodents and sheep, as well as in fish food [2,16,17,18,19,20,21]. In humans, the most common sites of isolation are the skin of the lower limbs, arms, head and nostrils.…”

Section: Discussionmentioning

confidence: 99%

A case of exudative pleuritis caused by Staphylococcus warneri

Szymański,

Skiba,

Piasecka

2023

Ann Agric Environ Med.

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This paper discusses the case of a patient with exudative bacterial pneumonia caused by Staphylococcus warneri. The patient had been abusing alcohol and nicotine for several decades, which should be considered an immunosuppressive factor. Staphylococcus warneri is part of the skin microbiome, but can also be a pathogenic agent in certain circumstances. Pleural fluid is an unusual site of isolation for the staphylococcus described. The literature contains case reports of arthritis, endocarditis, urinary tract infection or infection associated with continuous ambulatory peritoneal dialysis caused by Staphylococcus warneri. With the development of medicine, the phenomenon of immunosuppression is becoming more common, posing the threat of an increase in invasive infections caused by coagulase-negative staphylococci. In addition, an overly liberal use of antibiotics may contribute to the generation of multidrug resistance in these micro-organisms.

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Section: Discussionmentioning

confidence: 99%

A case of exudative pleuritis caused by Staphylococcus warneri

Szymański,

Skiba,

Piasecka

2023

Ann Agric Environ Med.

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“…A high percentage of Staphylococcus spp. isolates from bovine mastitis cases were described to be antimicrobial-resistant, depending on the pathogen species and the antibiotic used [ 16 ]. Staphylococcus aureus has been considered as among the most frequently isolated contagious pathogen in mastitis cases with poor cure rates and recurrent infections [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Intramammary Infusion of Micronised Purified Flavonoid Fraction (MPFF) in Mastitis-Diagnosed Dairy Cows Naturally Infected by Staphylococcus spp. in the Late Lactation

Gutiérrez-Reinoso,

Uquilla,

Guamaní

et al. 2023

Veterinary Sciences

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Infectious mastitis is the most prevalent health problem in dairy cattle that can result in permanent economic losses on dairy farms. The micronised purified flavonoid fraction (MPFF) is a biocompatible active polyphenolic compound derived from flavonoid glycosides which exhibits several antimicrobial, anti-inflammatory, and phlebotonic properties. The goal was to assess the effects of an alternative therapy for mastitis based on MPFF intramammary infusions in late lactation in dairy cows naturally infected by Staphylococcus spp. The California Mastitis Test (CMT scores) was performed to detect mastitis-positive quarters in twelve dairy farms. All cows were screened for immune response by measuring somatic cell counts (SCCs; cells/mL) in milk samples from each quarter. In addition, bacteriological identification, pathogenic bacterial isolates, and total bacterial counts (TBCs; CFU/mL) were assessed before (day 0, last milking day) and after (day 3 post-calving) MPFF application. Antimicrobial sensitivity patterns of the pathogenic isolated bacteria were evaluated. Finally, cure rates (%) were determined for each MPFF treatment. Around 15 mastitis-related genera were isolated. Staphylococcus aureus (25.2%) and coagulase-negative Staphylococci (CNS; 22.4%) were the most prevalent pathogens. No statistical differences were observed in SCCs and TBCs after low, medium, and high MPFF dose administration in S. aureus-positive mastitis cases (p > 0.05). However, differences were observed in SCCs and TBCs after medium and high MPFF dose administration in CNS-positive quarters (p < 0.05). The pathogenic bacteria isolate reduction after MPFF applications showed a dose-response fashion (p < 0.01) while isolates obtained from controls and low MPFF-treated quarters remained similar, irrespective of the pathogen (p > 0.05). Sensitivity patterns were variable, although S. aureus remained resistant, irrespective of the MPFF dose. However, CNS showed a dose-response sensitivity pattern. Finally, the cure rate (%) on day 3 post-partum improved significantly using medium and higher MPFF doses in CNS-positive quarters (p < 0.05). In conclusion, MPFF treatment was found to be more effective for CNS-positive cases in the late lactation due to noticeable dose-specific responses regarding somatic cells, bacterial counts, sensitivity patterns, and cure rates in dairy cattle.

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