Disposable non-enzymatic electrochemical glucose sensors based on screen-printed graphite macroelectrodes modified via a facile methodology with Ni, Cu, and Ni/Cu hydroxides are shown to accurately determine glucose in real human serum blood samples

Abstract

A three dimensional (3D) non-enzymatic glucose disposable electrochemical sensor based on screen-printed graphite macroelectrodes (SPEs), modified with nickel hydroxide (Ni(OH)2/SPE), copper hydroxide (Cu(OH)2/SPE) and mixed (Ni(OH)2/Cu(OH)2/SPE) microstructures were prepared by...

Heterostructural NiCo2O4 Nanocomposites for Nonenzymatic Electrochemical Glucose Sensing

“…Cu core shell nanosphere based non-enzymatic sensor can determinate 3-12 mM glucose, with detection limit of 1.45 mM [16]. Chelaghmia et al [17] proposed non-enzymatic disposable sensor relied on screen-printed graphite macroelectrodes (SPE), modified with Ni(OH) 2 , Cu(OH) 2 and Ni(OH) 2 /Cu(OH) 2 microstructures. Particularly, Ni(OH) 2 /Cu(OH) 2 /SPE demonstrated the lowest detection limit of 0.2 μM and could achieve blood glucose analysis.…”

In situ Growth of Ni(OH)2 Nanoparticles on 316L Stainless Steel Foam: An Efficient Three‐dimensional Non‐enzymatic Glucose Electrochemical Sensor in Real Human Blood Serum Samples

“…These shifts can be related to rapid electron transfer kinetics over this range of scan rates [55]. Besides that, a linear proportionality between peaks currents and the square root of scan rate was found (Figure 4b), indicating a diffusion‐controlled process over the Ni(OH) 2 /SSF‐316L electrode surface.…”

Fully automated station for testing, characterizing and modifying screen-printed electrodes

“…7,8 SPEs usually comprise working electrodes (WEs), reference electrodes (REs) and counter electrodes (CEs) on plastic, glass, paper or sintered Al 2 O 3 substrates. [9][10][11] They have been shown to be valuable tools in environmental, food, pharmaceutical and clinical laboratories and have even been utilized in point-of-care analytical devices. 5 Commercial producers have attempted to develop advanced electrochemical sensors and provide suitable accessories to help with handling high-throughput samples, with these sensors including magnetic trays, ow-through cells, and combined electrochemical and enzyme-linked immunosorbent assay (ELISA) multiwell plates.…”