Disease severity scoring systems in dermatology

Bilaç, Cemal; Şahin, Mustafa Turhan; Öztürkcan, Serap

doi:10.4274/turkderm.67799

Cited by 3 publications

(3 citation statements)

References 78 publications

(86 reference statements)

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“…A PASI score of 10 or higher defines the disease as moderate to severe and a candidate for systemic treatment. 13 In the statistical analysis of the study, the SPSS 21.0 program was used. Descriptive analyses were performed to calculate descriptive values such as frequency distributions, mean, standard deviation, median, minimum, maximum, and percentages.…”

Section: Methodsmentioning

confidence: 99%

Malnutrition Frequency and its Relationship with the Disease Severity in Geriatric Psoriasis Patients: A Cross Sectional Study

AYTİMUR,

AKÇİÇEK,

ERTAM SAĞDUYU

et al. 2024

Turkiye Klinikleri J Dermatol

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Whether psoriasis increases the frequency of malnutrition in the geriatric age group and whether malnutrition's frequency or severity and disease severity is related, remains unclear. This study aims to determine the frequency of malnutrition in geriatric psoriasis patients and identify associated factors. Material and Methods: Thirty two patients aged sixty and above treated at Psoriasis Clinic of Ege University Hospital between July 2019 and May 2021 were included in the study, administered survey forms, mini nutritional assessment (MNA), and Psoriasis Area Severity Index (PASI) were reported. MNA score of 24 and above indicate no malnutrition risk, 17-23.5 points suggest risk of malnutrition, and below 17 points indicate malnutrition. PASI score 10 and above categorize the disease as moderate-severe. SPSS 21.0 software was used. Chi-square test, Fisher's exact test for correlation analysis, multivariate logistic regression analysis were used to determine factors associated with malnutrition risk. Results: The average age of thirty-two psoriasis patients is 67.4 and 84.4% are male. Among the patients, analysis showed no statistically significant relationship between sociodemographic factors and MNA score, clinical findings and MNA score, or PASI values. According to PASI values, 15.6% of patients had a PASI of 10 or higher, 4 at risk of malnutrition had PASI below 10. Twenty three patients in normal MNA group had PASI below 10. Only normal patients and patients who were at risk of malnutrition were detected. Regression analysis showed that risk of malnutrition was 52.51 times higher in alcohol users (odds ratio: 52.5) (confidence interval=2.514-1096.76, p=0.011). Conclusion: No malnutrition cases were detected. As risk of malnutrition is found to be higher among alcohol users of geriatric psoriasis patients, further evaluation of its association with malnutrition will increase awareness for elder health.

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Section: Methodsmentioning

confidence: 99%

Malnutrition Frequency and its Relationship with the Disease Severity in Geriatric Psoriasis Patients: A Cross Sectional Study

AYTİMUR,

AKÇİÇEK,

ERTAM SAĞDUYU

et al. 2024

Turkiye Klinikleri J Dermatol

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“…Psoriasis severity was calculated using PASI 14 . Subjects were categorized: Mild (0‐5), moderate (6‐10), or severe (>10).…”

Section: Methodsmentioning

confidence: 99%

Correlation of metabolic syndrome with serum omentin‐1 and visfatin levels and disease severity in psoriasis and psoriatic arthritis

Dağdelen

Karadağ

Kasapoğlu

et al. 2020

Dermatologic Therapy

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Psoriasis and psoriatic arthritis (PsA) have been linked to metabolic syndrome (MS). The impact of adipokines on psoriasis, PsA, and MS pathogenesis has recently received investigative attention. A total of 80 subjects with psoriasis, 40 subjects with PsA, and 60 healthy controls were enrolled. Serum omentin and visfatin levels were measured, and MS presence was determined. PASI and DAS28 were used to measure disease severity for psoriasis and PsA, respectively. The prevalence of MS was determined to be 49% in psoriasis, 48% in PsA, and 28% in control groups. Rates were similar in psoriasis and PsA groups and was significantly greater when compared to control (P = .028). Diastolic blood pressure and waist circumference were significantly greater in the psoriasis group. Although the presence of MS positively correlated with age and disease duration in the psoriasis group, no significant relationships with PASI and DAS28 were found. Among all groups combined, there was no significant relationship with omentin and visfatin levels. In the psoriasis group, omentin and visfatin levels were greater in those with MS compared to those without MS. The relationships between omentin and visfatin levels with MS in patients with psoriasis and PsA has not yet been fully elucidated. These results suggest that elevated omentin and visfatin levels seen in psoriasis may be linked to MS rather than psoriasis itself. Additional research is needed to investigate the utility of these measurements as indicators of MS in patients with psoriasis.

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“…The PASI score is a scoring system in which the severity and extent of psoriasis disease are evaluated together, by which the size of the lesions in the head, upper extremities, lower extremities and trunk regions, and the severity of erythema induration and dandruff are evaluated (15). The sum of the scores in all 4 regions is expressed as a maximum of 72 points, with the increased scores representing the severe psoriasis case (15). NAPSI is a scoring method developed to determine the severity of nail involvement in psoriasis patients (16).…”

Section: Study Parametersmentioning

confidence: 99%

Comparison of quality of life, depression and fatigue in patients with psoriasis and psoriatic arthritis

Ketenci¹,

Uzuner²,

Bilgici³

2022

JECM

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Psoriatic arthritis (PsA) is a chronic inflammatory multisystemic disease. Limitations due to skin and joint involvement of the patients; can lead to negativie suffix in emotional state, social and physical activities. The aim of this study is to investigate the effects of parameters such as skin joint involvement and disease severity on factors such as fatigue, quality of life, depression, etc. in psoriasis and PsA patients. Thirty-four psoriasis and 48 PsA patients matched with each other in terms of age, sex, and other factors were included in the study. Disease severity was measured by Psoriasis Area Severity Index (PASI), Nail Psoriasis Severity Index (NAPSI), Disease Activity in Psoriatic Arthritis (DAPSA) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) scores. In order to determine the depression status, quality of life and fatigue levels of the patients, respectively; Beck Depression Inventory (BDI), Health Assessment Questionnaire (HAQ) and Functional Assessment of Chronic Illness Therapy - fatigue scale (FACIT) scores were used. SPSS 17 for statistical evaluation (SPSS Inc. Released 2007. SPSS for Windows, Version 17.0. Chicago, SPSS Inc.) software package was used for analyses. Written informed consent was obtained from all patients who were enrolled to the study. PsA patients were found to have worse quality of life scores than psoriasis patients who were similar in terms of age, gender and other demographic characteristics. (0.22±0.36-0-0.48±0.52 p=0.017 respectively). There was a strong correlation between DAPSA scores and HAQ scores of the cases in the PsA group (r:0 ,615 p<0.05). Likewise, disease activity measured by DAPSA was found to have moderate correlation with FACIT score, and weak but statistically significant correlation with BDI score. (r: -0.578 p<0.05 and r:0.346 p<0.001, respectively). No correlation was found between NAPSI-PASI scores and HAQ, BDI - FACIT scores in both the psoriasis and PsA groups. Both psoriasis and PsA affect the quality of life, and our findings suggest that this effect is more pronounced in PsA patients. Our study supports that; the disease severity in PsA patients is related to depression, bad quality of life and fatigue level.

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Disease severity scoring systems in dermatology

Cited by 3 publications

References 78 publications

Malnutrition Frequency and its Relationship with the Disease Severity in Geriatric Psoriasis Patients: A Cross Sectional Study

Malnutrition Frequency and its Relationship with the Disease Severity in Geriatric Psoriasis Patients: A Cross Sectional Study

Correlation of metabolic syndrome with serum omentin‐1 and visfatin levels and disease severity in psoriasis and psoriatic arthritis

Comparison of quality of life, depression and fatigue in patients with psoriasis and psoriatic arthritis

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