Direct pulp capping with a self-etching adhesive system: Histopathologic evaluation in dogs' teeth

The Effects of Hyaluronic Acid, Calcium Hydroxide, and Dentin Adhesive on Rat Odontoblasts and Fibroblasts

“…Products most often used for pulp capping are calcium hydroxide-based materials, glass ionomer cements, adhesive systems, and mineral trioxide aggregates (8)(9)(10)(11).…”

Pulpo-dentin complex response after direct capping with self-etch adhesive systems

“…Evaluation criteria for healing exposed pulp typically include the differentiation of odontoblast-like cells, the formation of a hard tissue barrier across the exposed area, and the absence of inflammation in the adjacent tissue [1][2][3][4][5][6][7][8]. Protection of the pulpo-dentin complex, under restorative material, involves the application of materials to dental tissues to avoid additional challenges to the pulp tissue by mechanical trauma, operating procedures, toxicity of the material used, and bacterial penetration due to microleakage.…”

“…Protection of the pulpo-dentin complex, under restorative material, involves the application of materials to dental tissues to avoid additional challenges to the pulp tissue by mechanical trauma, operating procedures, toxicity of the material used, and bacterial penetration due to microleakage. Numerous studies have shown that Ca(OH) 2 should be considered the gold standard for the treatment of pulp wounds [1][2][3][4][5][6], by stimulating the formation of dentin bridges and consequently leading to pulp healing, and thus providing high success rates for clinical procedures. However, Ca(OH) 2 has been reported to dissolve over time, and dentin bridges adjacent to the material may contain multiple tunnel defects that open to the underlying pulp.…”

“…In recent years, dentin bonding systems (DBSs) have been examined in humans [1,4,7,[12][13][14][15][16][17][18][19] and animals [2,5,[9][10][11][20][21][22][23][24][25][26][27][28][29] as potential direct capping materials due to their superior ability to adhere to demineralised dentin tissues. Hybridisation of DBSs and diffusion of adhesives into the dentin tubules may protect the dentin against bacterial leakage and reduce secondary pulpal inflammation.…”

“…Several experimental studies [2,5,7] have evaluated histopathologically the response of pulp capping with the Adper Prompt L-Pop system. Dentin bridge formation was not observed, and the remaining pulp tissue exhibited severe inflammatory alterations and areas of necrosis [2,5].…”