Direct detection of Pb2+ and Cd2+ in juice and beverage samples using PDMS modified nanochannels electrochemical sensors

Li, Gangfeng; Belwal, Tarun; Luo, Zisheng; Li, Yintao; Li, Li; Xu, Yanqun; Lin, Xingyu

doi:10.1016/j.foodchem.2021.129632

Cited by 38 publications

(21 citation statements)

References 37 publications

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“…Among the developed SSN, vertically ordered mesoporous silica nanochannel film (VMSF) exhibits high chemical and thermal stability, ordered and vertically aligned nanochannels (nanopores), uniform pore size distribution, high pore density, and ease of modification ( Nasir et al, 2018 ; Jiokeng et al, 2019 ; Ullah et al, 2021 ; Walcarius, 2021 ). The ultrasmall (usually 2–3 nm) and high-density (up to 4∼8 × 10 12 /cm 2 ) nanochannel arrays make it possible to significantly improve the sensor performance as electrode modification materials ( Mi et al, 2020 ; Li et al, 2021a ; Asadpour et al, 2021 ; Li et al, 2021b ; Xiao et al, 2021 ). On the one hand, a large number of silanol groups (Si-OH) with low pKa (∼2) endow the VMSF with a negatively charged surface, which can accelerate the transfer of positively charged molecules to the electrode surface, leading to a significant enrichment effect.…”

Section: Introductionmentioning

confidence: 99%

A Flexible Electrochemiluminescence Sensor Equipped With Vertically Ordered Mesoporous Silica Nanochannel Film for Sensitive Detection of Clindamycin

Wei

et al. 2022

Front. Chem.

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Fast, convenient, and highly sensitive detection of antibiotic is essential to avoid its overuse and the possible harm. Owing to enrichment effect and antifouling ability of ultrasmall nanochannels, the vertically ordered mesoporous silica nanochannel film (VMSF) has great potential in the development of the facile electrochemiluminescence (ECL) sensor for direct and sensitive analysis of antibiotics in complex samples. In this study, we demonstrated a flexible ECL sensor based on a cost-effective electrode covered with a VMSF for sensitive detection of clindamycin. Polyethylene terephthalate coated with indium tin oxide (PET-ITO) is applied as a flexible electrode to grow VMSF using the electrochemically assisted self-assembly (EASA) method. The negatively charged VMSF nanochannels exhibit significant enrichment toward the commonly used cationic ECL luminophores, tris(2,2-bipyridyl) dichlororuthenium (II) (Ru (bpy)32+). Using the enhanced ECL of Ru (bpy)32+ by clindamycin, the developed VMSF/PET-ITO sensor can sensitively detect clindamycin. The responses were linear in the concentration range of 10 nM–25 μM and in the concentration range of 25–70 μM. Owing to the nanoscale thickness of the VMSF and the high coupling stability with the electrode substrate, the developed flexible VMSF/PET-ITO sensor exhibits high signal stability during the continuous bending process. Considering high antifouling characteristic of the VMSF, direct analysis of clindamycin in a real biological sample, human serum, is realized.

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Section: Introductionmentioning

confidence: 99%

A Flexible Electrochemiluminescence Sensor Equipped With Vertically Ordered Mesoporous Silica Nanochannel Film for Sensitive Detection of Clindamycin

Wei

et al. 2022

Front. Chem.

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“…Recently, porous materials as functional building blocks have been widely used for the construction of high-performance sensors, taking advantage of their ease of hybridization ( Cui et al, 2020 ; Cui et al, 2021 ; Duan et al, 2021 ; Liu et al, 2022 ), efficient enrichment ( Liang et al, 2021 ; Yan et al, 2021 ), and rapid mass transfer ( Zhou et al, 2022a ; Gong et al, 2022 ). Especially, vertically-ordered mesoporous silica films (VMSF) have been proven to be powerful preconcentration materials for electrochemical detection of metal ions, such as Cu 2+ ( Cheng et al, 2018 ; Lu et al, 2018 ), Hg 2+ ( Lu et al, 2018 ), Ag + ( Herzog et al, 2013 ), Pb 2+ ( Fernández et al, 2014 ; Cheng et al, 2018 ; Li et al, 2021 ), and Cd 2+ ( Cheng et al, 2018 ; Lu et al, 2018 ; Li et al, 2021 ). VMSF prepared by electrochemically assisted self-assembly (EASA) ( Walcarius et al, 2007 ) and Stöber solution growth ( Teng et al, 2012 ) methods possess a perpendicularly regular channel structure with uniform pore size, negatively charged channel walls and high porosity, which are very suitable for the construction of electrochemical sensors for direct analysis of various analytes in complex samples, including biomolecules ( Li et al, 2014 ; Ma et al, 2022a ; Ma et al, 2022b ; Zhu et al, 2022 ), drug molecules ( Wang et al, 2022 ; Wei et al, 2022 ), organic pollutants ( Yan et al, 2021 ), metal ions ( Cheng et al, 2018 ; Lu et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Vertically-Ordered Mesoporous Silica Films for Electrochemical Detection of Hg(II) Ion in Pharmaceuticals and Soil Samples

et al. 2022

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Rapid and simple determination of mercury ion (Hg2+) in pharmaceuticals and soil samples is vital for human health and the environmental monitoring. Vertically-ordered mesoporous silica films (VMSF) supported by the indium tin oxide (ITO) electrode surface were prepared by electrochemically assisted self-assembly method and utilized for electrochemical detection of Hg2+. Owing to the negatively charged channel walls and ultrasmall pore diameter, VMSF displays obvious cationic selectivity and has highly electrostatic interaction for Hg2+, giving rise to the strong electrochemical signals. By recording the anodic stripping signals of adsorbed Hg2+ using differential pulse voltammetry, quantitative detection of Hg2+ was achieved with a wide linear range (0.2 μM–20 μM) and a low limit of detection (3 nM). Furthermore, considering the anti-fouling and anti-interference capacity of VMSF, the proposed VMSF/ITO sensor has been successfully applied to detect Hg2+ in pharmaceuticals and soil samples without tedious pretreatment processes of samples.

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“…Porous materials have aroused increasing attention in the development of various high-performance sensors (19)(20)(21), drug delivery systems (22), and electrocatalysts (23). Vertically ordered mesoporous silica film (VMSF) as an attractive electrode modification material has ultrasmall and uniform pore diameter, high porosity, and ordered silica nanochannel perpendicular to the electrode substrate, exhibiting high permeability and excellent molecular selectivity (e.g., size, charge, hydrophobicity, and isomer) and showing a wide range of applications in direct electroanalysis of complex samples (24)(25)(26). There are three main methods for the growth of VMSF on solid electrodes, including Stöber-solution (27)(28)(29), biphasic stratification (30), and electrochemically assisted selfassembly (EASA) (31)(32)(33)(34) methods, of which EASA method can complete the modification in a few seconds and the obtained VMSF has more regular mesopores.…”

Section: Introductionmentioning

confidence: 99%

Silica nanochannels boosting Ru(bpy)32+-mediated electrochemical sensor for the detection of guanine in beer and pharmaceutical samples

et al. 2022

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Vertically ordered mesoporous silica film (VMSF) with uniform mesoporous channels perpendicular to electrode substrate has a wide range of applications in direct electroanalysis of complex samples. However, the detection of nucleic acid bases is difficult to realize at the commonly used VMSF-modified indium tin oxide (VMSF/ITO) electrode due to the high overpotentials of underlying ITO for many small organic molecules. In this work, we demonstrated an electrochemical method for the sensitive detection of guanine (G) by integration of VMSF/ITO and tris(2,2′-bipyridine) ruthenium (II) [Ru(bpy)32+] redox mediator. Ru(bpy)32+ electrostatically accumulated by VMSF is able to act as an electron shuttle between G and underlying ITO surface, showing electrocatalytic oxidation of G and enabling the quantitative determination of G with a limit of detection (LOD) of 0.058 μM and a limit of quantitation (LOQ) of 0.2 μM. Electrochemical detection performance for G could be regulated by changing the pH of the supporting electrolyte and the content of Ru(bpy)32+, achieving a wide dynamic linear range from 0.2 to 10 μM (R2 = 0.999), 2 to 100 μM (R2 = 0.999), and 10 to 500 μM (R2 = 0.998). Furthermore, owing to the good anti-fouling and anti-interference ability of VMSF, this simply sensing strategy can be applied to the direct and rapid detection of G in beer samples, and the detection of ganciclovir (G analog) content in ganciclovir eye drops.

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Direct detection of Pb2+ and Cd2+ in juice and beverage samples using PDMS modified nanochannels electrochemical sensors

Cited by 38 publications

References 37 publications

A Flexible Electrochemiluminescence Sensor Equipped With Vertically Ordered Mesoporous Silica Nanochannel Film for Sensitive Detection of Clindamycin

A Flexible Electrochemiluminescence Sensor Equipped With Vertically Ordered Mesoporous Silica Nanochannel Film for Sensitive Detection of Clindamycin

Vertically-Ordered Mesoporous Silica Films for Electrochemical Detection of Hg(II) Ion in Pharmaceuticals and Soil Samples

Silica nanochannels boosting Ru(bpy)32+-mediated electrochemical sensor for the detection of guanine in beer and pharmaceutical samples

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