Understanding brain science helps in navigating the rough terrain of diverse workforce in organizations. Human potential in itself has infinite capabilities to bring in real change. Neuro studies focused on neurodiverse people facilitate exploring the untapped potential of the people with neurological differences such as autism, dyslexia, ADHD, and other such conditions. These are in reality just natural variations of the human brain that as a society we should be accepting, not as individuals but also as organizations. This chapter reflects upon how neuro-inclusive workspaces can be created to unlock the potential of a neurodiverse workforce. A factor matrix of neurodiversity helps to understand the change that is required in the organizational system and approach neurodiverse employees' engagement. Thus, exploring the avenues and challenges in front of leadership makes organizations more diverse and effective.