Digital tomosynthesis in breast imaging.

Niklason, Loren T.; Christian, Bradley T.; Niklason, Laura E.; Kopans, Daniel B.; Castleberry, D.E.; Opsahl-Ong, Beale; Landberg, Cynthia E.; Slanetz, Priscilla J.; Giardino, Angela; Moore, Richard H.; Albagli, Douglas; DeJule, M C; Fitzgerald, P F; Fobare, D F; Giambattista, Brian W.; Kwasnick, R F; Liu, J; Lubowski, S J; Possin, G. E.; Richotte, J F; Wei, C.; Wirth, R F

doi:10.1148/radiology.205.2.9356620

Cited by 703 publications

(373 citation statements)

References 0 publications

Supporting

Mentioning

361

Contrasting

Unclassified

Order By: Relevance

“…147 Increasingly, the synthesis of 3-dimensional (3D) images from DBT and the use of combined 2D and 3D improve detection of breast cancer in mammographically dense breasts. 148,149 Studies have reported 7.2% -53% increase in cancer detection and 20% -59% reduction in recall rates with supplemental DBT. 31,44,45,150,151 Importantly, radiation dose to the dense tissue is lower for DBT than digital mammography (DM) for dense breasts; 43 therefore DBT is preferable to DM in terms of performance and dose, albeit it appears women with fatty breasts get higher dose on DBT.…”

Section: Imaging the Dense Breastmentioning

confidence: 99%

Breast composition: Measurement and clinical use

Ekpo¹,

Hogg²,

Highnam³

et al. 2015

Radiography

View full text Add to dashboard Cite

Breast density is a measure of the extent of radiodense fibroglandular tissue in the breast. The risk of developing breast cancer and the risk of missing cancer at screening rise with higher breast density. In this paper, the historical background to breast density measurement is outlined and current evidence based practice is explained. The relevance of breast density knowledge to mammographic practice and image interpretation is considered in the light of clinical assessment and notification of mammographic breast density (MBD). The current work also discusses risk stratification for decisionmaking regarding screening frequency and better modalities for earlier detection of breast cancer in the dense breast. Automated volumetric approaches are explained while ultrasound, digital breast tomosynthesis, molecular breast imaging, and magnetic resonance imaging are introduced as valuable adjuncts to digital mammography for imaging the dense breast. The work concludes on the important note that screened women should be notified of their breast density, and such notification should be accompanied with clear and adequate information about breast density and cancer risk, strategies associated with lower MBD, as well as best screening intervals and pathways for women with dense breasts. Adoption of these strategies may be crucial to early detection and treatment of cancer and improving survival from the disease.

show abstract

Section: Imaging the Dense Breastmentioning

confidence: 99%

Breast composition: Measurement and clinical use

Ekpo¹,

Hogg²,

Highnam³

et al. 2015

Radiography

View full text Add to dashboard Cite

show abstract

“…Digital tomosynthesis (DT) combines the benefits of digital imaging [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] with the tomographic benefits of computed tomography. The DT approach can be easily implemented in conjunction with radiography at reduced radiation doses and cost.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Reconstruction Algorithms for Decreasing the Exposure Dose During Digital Tomosynthesis for Arthroplasty: a Phantom Study

et al. 2016

View full text Add to dashboard Cite

To explore the possibility of decreasing the radiation dose during digital tomosynthesis (DT) for arthroplasty, we compared the image qualities of several reconstruction algorithms, such as filtered back projection (FBP) and two iterative reconstruction (IR), methods maximum likelihood expectation maximization (MLEM) and the simultaneous iterative reconstruction technique (SIRT) under different radiation doses. The three algorithms were implemented using a DT system and experimentally evaluated by contrast-to-noise ratio (CNR), artifact spread function (ASF), and power spectrum measurements on a prosthesis phantom. The CNR and ASF data were statistically analyzed by a one-way analysis of variance. The effectiveness of each technique for enhancing the visibility of the prosthesis phantom was quantified by the CNR (reference dose vs. 20 % reduced dose in FBP, P = 0.62; reference vs. 37 % reduced dose in FBP, P = 0.16; reference vs. 55 % reduced dose in FBP, P < 0.05; reference vs. 20 % reduced dose in IR, P = 0.92; reference vs. 37 % reduced dose in IR, P = 0.40; reference vs. 55 % reduced dose in IR, P < 0.05) and ASF (reference dose vs. 20 % reduced dose in FBP, P = 0.25; reference vs. 37 and 55 % reduced dose in FBP, P < 0.05; reference vs. 20 % reduced dose in IR, P = 0.16; reference vs. 37 and 55 % reduced dose in IR, P < 0.05). The power spectra under the reference and reduced doses are equivalent. In this phantom study, the radiation dose of the reference dose could be decreased by 20 % with FBP and IR for consideration of common factors.

show abstract

“…DBT has been considered as a promising technique to reconstruct three-dimensional information of the breast to improve early breast cancer detection. Compared with standard mammography two-dimensional imaging techniques, DBT improves conspicuousness of structures by removing the visual clutter associated with overlying anatomy (Dobbins III and Godfrey, 2003;Chen et al, 2005;Niklason et al, 1997;Wu et al, 2003;Chen et al, 2007;Bissonnette et al, 2005;Zhang et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

“…Grant (1972) developed conventional SAA tomosynthesis to reconstruct planes through the subject 40 years Until now, several DBT image reconstruction algorithms have been proved effectively by different research groups. In 1997, Niklason and colleagues reported image-stretching SAA technique for mammography to investigate a tomosynthesis method with the X-ray tube moved in an arc above the stationary breast and detector (Niklason et al, 1997). Suryanarayana et al (2000Suryanarayana et al (2001 reported research on breast tomosynthesis with Webber's Tuned-Aperture Computed Tomography (TACT) algorithm in 2000.…”

Section: Introductionmentioning

confidence: 99%

“…It also works as the foundation of a few other algorithms, including Niklason and colleagues' image stretching SAA (Niklason et al, 1997), TACT (Suryanarayanan et al, 2000(Suryanarayanan et al, , 2001, MITS (Chen et al, 2004, etc. Currently, most commercial breast tomosynthesis prototype devices apply the isocentric tube motion geometry where the X-ray tube moves along an arc above the detector (Wu et al, 2003;Bissonnette et al, 2005;Zhang et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impulse response and Modulation Transfer Function analysis for Shift-And-Add and Back Projection image reconstruction algorithms in Digital Breast Tomosynthesis (DBT)

Chen

Dobbins

2008

IJFIPM

View full text Add to dashboard Cite

Breast cancer is second only to lung cancer as the leading cause of non-preventable cancer death in women. Digital Breast Tomosynthesis (DBT) is a promising technique to improve early breast cancer detection. In this paper, we present the impulse response and Modulation Transfer Function (MTF) analysis to quantitatively compare Shift-And-Add (SAA) and point-by-point Back Projection (BP) three-dimensional image reconstruction algorithms in DBT. A Filtered Back Projection (FBP) deblurring algorithm based on point-by-point BP was used to demonstrate deblurred tomosynthesis images.

show abstract

Digital tomosynthesis in breast imaging.

Abstract: Digital mammographic systems make breast tomosynthesis possible. Tomosynthesis may improve the specificity of mammography with improved lesion margin visibility and may improve early breast cancer detection, especially in women with radiographically dense breasts.

Cited by 703 publications

References 0 publications

Breast composition: Measurement and clinical use

Breast composition: Measurement and clinical use

Comparison of Reconstruction Algorithms for Decreasing the Exposure Dose During Digital Tomosynthesis for Arthroplasty: a Phantom Study

Impulse response and Modulation Transfer Function analysis for Shift-And-Add and Back Projection image reconstruction algorithms in Digital Breast Tomosynthesis (DBT)

Contact Info

Product

Resources

About