Fig. 1. One of the applications of the proposed end-to-end computational camera design paradigm is achromatic extended depth of field. When capturing an image with a regular singlet lens (top left), out-of-focus regions are blurry and chromatic aberrations further degrade the image quality. With our framework, we optimize the profile of a refractive optical element that achieves both depth and chromatic invariance. This element is fabricated using diamond turning (right) or using photolithography. After processing an image recorded with this optical element using a simple Wiener deconvolution, we obtain an all-in-focus image with little chromatic aberrations (top center). Point spread functions for both the regular lens and the optimized optical element are shown in the bottom. In this paper, we explore several applications that demonstrate the efficacy of our novel approach to domain-specific computational camera design.