Dietary assessment in five cases of allergic reactions due to gastroallergic anisakiasis

Abstract

In gastroallergic anisakiasis, the antigens of the live parasite probably cause the allergic symptoms. Patients with this disease can tolerate deep-frozen seafood, in which the parasites are dead.

Oral inoculation of live or dead third-stage larvae of Anisakis simplex in rats suggests that only live larvae induce production of antibody specific to A. simplex

“…2). This result supports the previous finding (Alonso et al 1999;Alonso-Gomez et al 2004) that the ingestion of frozen fish is safe in anisakiasis. Combining the data presented in Figs.…”

Diagnosing Human Anisakiasis: Recombinant Ani s 1 and Ani s 7 Allergens versus the UniCAP 100 Fluorescence Enzyme Immunoassay

“…Indeed, on the basis of previous reports (9,27), it could be argued that in addition to Anisakis infections, CAP FEIA detects IgE antibodies induced by free Anisakis allergens that are present in fish contaminated with this parasite and categorizes the patients as positive. However, this hypothesis appears unlikely, considering the negative results obtained in provocation test studies carried out on sensitized patients, using frozen (1,2,14), freeze-dried (32), or excretory-secretory (6) antigens, as well as in experiments conducted in a murine model of anaphylaxis (7). In consequence, it appears more likely that the large number of positive results obtained with CAP FEIA is the result of the detection of IgE antibodies induced by other allergens that share common epitopes with Anisakis allergens, as previously reported (15,18,29).…”

Prevalence and Mean Intensity of Anisakidae Parasite in Seafood Caught in the Mediterranean Sea Focusing on Fish Species at Risk of Being Raw-consumed. A Meta Analysis and Systematic Review

“…The risk of allergic reactions after nonviable anisakids fish ingestion is a matter of some concern. Some authors reported that sensitized subjects did not show any symptom after administration of dead larvae (Alonso-Gómez et al, 2004;Sastre et al, 2000;Alonso et al, 1999). On the contrary, other researchers showed that 13 of 64 subjects with Anisakis sensitization history had adverse reaction after eating properly (Moneo et al, 2007).…”