Diet selection in immunologically manipulated mice

Teixeira, Gerlinde Agate Platais Brasil; Paschoal, Patrícia Olaya; Oliveira, Victor De; Pedruzzi, Monique M.B.; Campos, Sylvia Maria Nicolau; Andrade, Luiz Antonio Botelho; Nóbrega, Alberto

doi:10.1016/j.imbio.2007.08.001

Cited by 11 publications

(13 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The features of this model are prominent mononuclear leukocyte infiltrate and lamina propria edema and larger numbers of goblets cells inducing architectural changes such as, villous atrophy and crypt hyperplasia. Clinically, these animals present significant weight loss which can be explained by the histological findings of the gut, which in turn may be the cause of lower food intake (Teixeira et al, 2008b), and a lower absorption rate (Teixeira et al, 2008a, in press). These are in agreement to the typical signs seen in human celiac disease (gluten enteropathy), and which are observed in other foodinduced enteropathies.…”

Section: Discussionmentioning

confidence: 99%

“…These are in agreement to the typical signs seen in human celiac disease (gluten enteropathy), and which are observed in other foodinduced enteropathies. We have also described that when immunized animals are given the choice, they avoid the allergenic foodstuff eating the other components of the diet and consequently do not develop gut alterations (Teixeira et al, 2008b).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Food allergy/hypersensitivity: Antigenicity or timing?

et al. 2009

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Food allergy/hypersensitivity: Antigenicity or timing?

et al. 2009

Self Cite

View full text Add to dashboard Cite

“…A mouse model of gut inflammation developed by Teixeira et al (19) was used in the present study. Briefly, adult male C57BL/6 mice bred in the local animal facility of Federal Fluminense University (Rio de Janeiro, Brazil) were given free access to food and water.…”

Section: Methodsmentioning

confidence: 99%

Comparison between digital and optical microscopy: Analysis in a mouse gut inflammation model

et al. 2017

View full text Add to dashboard Cite

Abstract. Virtual microscopy is currently widely used for various purposes, such as teaching, archiving, collaborations and research. Although the cost of this technique has reduced, it continues to be expensive for the majority of laboratories in developing countries. The Graduate Program in Pathology at the Federal Fluminense University (Niterói, Brazil) has acquired equipment for virtual microscopy. However, this novel method faced prejudice, as students and technicians were skeptical about its reliability. Thus, the aim of the current study was to evaluate whether virtual microscopy is a reliable method of analysis for our research. Thus, a mouse gut inflammation model developed by our research group was used in the present study. Analysis was performed using optical microscopy and digital imaging using the APERIO scanning system and the ImageScope ® software. Intestinal epithelial cells (IECs), intra epithelial leucocytes (IEL), and villi number and area were evaluated. No significant differences were observed in villi number, IEC and IEL; however, the villi area was significantly smaller when measured using the computer. Thus, the present study indicates that virtual microscopy is a trustworthy method for research purposes.

show abstract

“…Peanut seeds were minced in an electrical coffee grinder sieved and defatted with ether (Teixeira et al, 2008). To the defatted seed preparation, extraction buffer (Sodium borate, 0,0125M, SDS 1%, Mercaptoetanol 1% -pH 10) was added, maintaining a 1:10 (w/v) ratio.…”

Section: Peanut Protein Extracts (Ppe)mentioning

confidence: 99%