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citations
Cited by 13 publications
(10 citation statements)
references
References 24 publications
(24 reference statements)
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“…In this work, along with the assessment of clinical aspects during the induction of food allergy and gut inflammation, gut histopathology was performed. Similar to previous findings of our group, the results obtained led to an array of histological alterations spanning from normal histology (control animals) to severe inflammation of the duodenum (allergic group) . The pathophysiological changes induced by the inflammatory response led to alterations both in the cell count and in the villus architecture.…”
Section: Discussionsupporting
confidence: 87%
See 1 more Smart Citation
“…In this work, along with the assessment of clinical aspects during the induction of food allergy and gut inflammation, gut histopathology was performed. Similar to previous findings of our group, the results obtained led to an array of histological alterations spanning from normal histology (control animals) to severe inflammation of the duodenum (allergic group) . The pathophysiological changes induced by the inflammatory response led to alterations both in the cell count and in the villus architecture.…”
Section: Discussionsupporting
confidence: 87%
“…Similar to previous findings of our group, the results obtained led to an array of histological alterations spanning from normal histology (control animals) to severe inflammation of the duodenum (allergic group). 19,40,41 The pathophysiological changes induced by the inflammatory response led to alterations both in the cell count and in the villus architecture. No animal presented classical anaphylaxis symptoms, such as convulsions, wheezing, laboured respiration or pilar erecti.…”
Section: Discussionmentioning
confidence: 99%
“…The immunological status of the gut, as has been previously demonstrated by our group, is essential to induce either allergy or tolerance after the initial contact of the food with the mucosa. [26] Our data agree with those of the literature [27,28] regarding the pH of the buffer used in the extraction of peanut proteins -neutral pH is more efficient.…”
Section: Immunogenicity/immunoreactivitysupporting
confidence: 92%
“…Only to site a few of the potential influencers of allergenicity are: the food matrix [23], protein stability during processing [25], and the immunological status of the entry port [26]. Food matrix can be defined as the way the chemical components of food (protein, fatty acids, carbohydrates, and micronutrients) interact to establish the structural organization from microscopic to macroscopic scales.…”
Section: Immunogenicity/immunoreactivitymentioning
confidence: 99%
“…Previous studies from our group reported the inflammatory milieu of the gut of allergic animals submitted to oral challenge, as well as the normal millieu of the gut of allergic animals that were not submitted to oral challenge (23,24). The analysis performed in these papers used either OM or DM; however, no comparison was performed.…”
Section: Discussionmentioning
confidence: 99%