Die retothelialen H�moblastosen

Leukemic Reticulosis and Allied Disorders

“…[4][5][6][7][8][9][10][11][12][13][14][15][16] From the tritaristic viewpoint of leukopoiesis, leukemic reticuloendotheliosis means monocytic leukemia, and to unitarians it means stem cell leukemia. [17][18][19][20] Moreover, the fact that some American authors use the term "stem cell leukemia" in the sense of acute undifferentiated leukemia, and the presence of reactive reticulosis in association with various leukemias makes the concept confusing.…”

Concept of Reticuloendotheliosis

“…It is the purpose of this paper, therefore, to describe in detail the results which so far have been obtained and to discuss these problems. Relationship of the reticuloendotheliosis to stem cell leukemia and other allied proliferative disorders blood cell According to the monophyletic school, 15,18,29,34,40,41,56,58 the R.E. cells are stated to be identical with undifferentiated mesenchymal cells and thus to be totipotential, giving rise under proper stimulation to any other type of blood cell, whether erythrocyte or leukocyte, lympocyte or monocyte.…”

“…They emphasized that leukemic reticuloendotheliosis was identical with stem cell leukemia7, 8,12,19,20,26,27,34,35,42,56,71 and this thought is still predominant at the present time. ',", 14,18,24,29,36,38,39,57,61,75,78,80 Such cases as myeloreticulosis presented by Benecke,12 lymphoreticulosis by Apitz,7 or "polyblastische Retikulose" by Lubbers56 are also e xplained based on the monophyletic viewpoint.…”

The Morphological Determination of the Retothelial Syatem and its Pathogenetic Importance

“…Performing a causalanalytic experiment is a very difficult problem in medicine, particularly in human pathology, as its interpretation is too easily affected by an inclination to draw relative conclusions. However, if, forr example, an infusion of polyvinyl pyrrolidone evokes in man and experimental animals the same picture of kollidon storage, so far as position and amount are concerned (Fresen and Weese) 27), then it provides a basis for such an analytical experiment. It also allows a proper evaluation of the results of storage experiments with cerebrosides (Kimmerstiel and Laas)49) and sphingomyelin (Beumer and Gruber)13) with regard to thesauropathies in man, and the avoidance of misleading analogous conclusions in understanding and differentiating this cell system.…”