Die arteriellen Blutgaspartialdrücke und ihre Beziehungen zu Alter und anthropometrischen Grössen

F, Hertle; Goerg, R; Lange, H J

doi:10.1159/000192800

Cited by 30 publications

(13 citation statements)

References 15 publications

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“…Using these norms, we attempted to minimize the num ber of false pathological findings. Lower normal P a0 2 values reported in the liter ature are obtained from capillary blood [Hertle et al, 1971]. The effect of age on P a02 and (A-a)02 [Sorbini et al, 1968;Raine and Bishop, 1963;Hertle et al, 1971;Diament et al, 1969] could not be demonstrated in our patients.…”

Section: Discussioncontrasting

confidence: 70%

“…Lower normal P a0 2 values reported in the liter ature are obtained from capillary blood [Hertle et al, 1971]. The effect of age on P a02 and (A-a)02 [Sorbini et al, 1968;Raine and Bishop, 1963;Hertle et al, 1971;Diament et al, 1969] could not be demonstrated in our patients. lebavy/Fabián/Henzlová/Belán To our knowledge, pulmonary gas ex change in patients with stable IHD in rela tion to the degree of involvement of the coronary system and left ventricular func tion has not been reported in the literature.…”

Section: Discussioncontrasting

confidence: 70%

“…The age-related norms for healthy individuals differ from author to au thor [Hertle et al, 1971]. The difference in mean normal values reported in the litera ture ranges from 15 to 20 mm Hg [Hertle et al, 1971;Raine and Bishop, 1963]. We chose the normal values of Sorbini et al [1968] as they were the lowest values ob tained during arterial puncture.…”

Section: Discussionmentioning

confidence: 99%

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Pulmonary Gas Exchange in Candidates for Surgical Treatment of Ischaemic Heart Disease

Jebavý¹,

J²,

Henzlova³

et al. 1978

Respiration

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The spirometry and pulmonary gas exchange in 38 patients with ischaemic heart disease (IHD), selected for direct revascularization of the myocardium (or combined with left ventricular aneurysmectomy), were examined on the basis of clinical investigation and coronary arteriography. Elevated left ventricular end-diastolic pressure was found in 40% at rest and in more than 50% of patients during exercise. Vital capacity was entirely within the normal limits. A relation was found between the period of time since the first acute myocardial infarction. In 20% of the patients the forced expiratory volume was below the predicted normal, but the decrease was not significant. A mild arterial hypoxaemia was found in 64% of patients at rest and in 70% during exercise; 79% showed an elevated alveolar arterial oxygen gradient. The abnormalities did not depend on the degree of coronary artery and left ventricular involvement nor on the haemodynamic parameters. However, a certain relation to history of cigarette smoking, which appears to affect pulmonary gas exchange more than IHD, was observed. The degree of respiratory disturbance does not in any way influence the proposed surgical treatment.

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Section: Discussioncontrasting

confidence: 70%

Section: Discussioncontrasting

confidence: 70%

Section: Discussionmentioning

confidence: 99%

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Pulmonary Gas Exchange in Candidates for Surgical Treatment of Ischaemic Heart Disease

Jebavý¹,

J²,

Henzlova³

et al. 1978

Respiration

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“…2). Hypercapnia (Pa,CO 2 w43 mmHg) [20] at peak exercise was present in 7/23 of the non-FL patients and in 21/29 of the FL patients (pv0.005). In FL patients, there was a significant fall in Pa,O 2 from rest to peak exercise (pv0.05), whereas in non-FL patients the Pa,O 2 did not change significantly.…”

Section: Resultsmentioning

confidence: 94%

Breathing pattern and gas exchange at peak exercise in COPD patients with and without tidal flow limitation at rest

et al. 2001

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Expiratory flow limitation (FL) at rest is frequently present in chronic obstructive pulmonary disease (COPD) patients. It promotes dynamic hyperinflation with a consequent decrease in inspiratory capacity (IC). Since in COPD resting IC is strongly correlated with exercise tolerance, this study hypothesized that this is due to limitation of the maximal tidal volume (VT,max) during exercise by the reduced IC. The present study investigated the role of tidal FL at rest on: 1) the relationship of resting IC to VT,max; and 2) on gas exchange during peak exercise in COPD patients.Fifty-two stable COPD patients were studied at rest, using the negative expiratory pressure technique to assess the presence of FL, and during incremental symptomlimited cycling exercise to evaluate exercise performance.At rest, FL was present in 29 patients. In the 52 patients, a close relationship of VT,max to IC was found using non-normalized values (r~0.77; pv0.0001), and stepwise regression analysis selected IC as the only significant predictor of VT,max. Subgroup analysis showed that this was also the case for patients both with and without FL (r~0.70 and 0.76, respectively). In addition, in FL patients there was an increase (pv0.002) in arterial carbon dioxide partial pressure at peak exercise, mainly due to a relatively low VT,max and consequent increase in the physiological dead space (VD)/VT ratio. The arterial oxygen partial pressure also decreased at peak exercise in the FL patients (pv0.05).In conclusion, in chronic obstructive pulmonary disease patients the maximal tidal volume, and hence maximal oxygen consumption, are closely related to the reduced inspiratory capacity. The flow limited patients also exhibit a significant increase in arterial carbon dioxide partial pressure and a decrease in arterial oxygen partial pressure during peak exercise.

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“…Statistisch auffällige oder gesicherte Korrelatio nen finden sich weiterhin zum FEVi.o und zu Grössen des respiratorischen Gasaustausches, nämlich Pa02 und AaDc>2. Da diese Grössen aber ebenfalls Beziehungen zu Alter und anthropometrischen Daten aufweisen [7], wurde, um Scheinkorrelationen zu vermeiden [9] [8].…”

Section: Diskussionunclassified

Vergleichende Bestimmung des Transferfaktors für Kohlenmonoxyd mit der Single-breath- und der Steady-state-Methode

Löllgen¹,

Smidt²,

Nieding³

et al. 1974

Respiration

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Die arteriellen Blutgaspartialdrücke und ihre Beziehungen zu Alter und anthropometrischen Grössen

Cited by 30 publications

References 15 publications

Pulmonary Gas Exchange in Candidates for Surgical Treatment of Ischaemic Heart Disease

Pulmonary Gas Exchange in Candidates for Surgical Treatment of Ischaemic Heart Disease

Breathing pattern and gas exchange at peak exercise in COPD patients with and without tidal flow limitation at rest

Vergleichende Bestimmung des Transferfaktors für Kohlenmonoxyd mit der Single-breath- und der Steady-state-Methode

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