Die Anwendung von Propanidid in der Gynäkologie

Histamine Release in Man by Propanidid and Thiopentone: Pharmacological Effects and Clinical Consequences

“…The preceding survey shows, however, that these incidents are in no way specific for both anaesthetics, but are described for many drugs used during anaesthesia. With the use of propanidid, however, the following authors have reported incidents during narcosis with clinical symptoms of anaphylactoid or allergic reactions: Beck, 1965;Michel 1965;Radway, 1965;Manz and Frank, 1969;Kay, 1969;Doenicke and Lorenz, 1970;Johns, 1970;Dannemann and Lubke, 1970;Kriiger, 1970. Using thiopentone, the following case reports were published: Hunter, 1943;Moore, 1946;Hayward and Kiester, 1957;Strunk, 1962;Shinohara and Inamoto, 1965;Currie et al, 1966;Carrie and Buchanan, 1967;Anderton and Hopton, 1968. As an explanation for these anaphylactoid and allergic reactions, different mechanism must be considered:…”