Diastereoselective three-component Mannich reaction catalyzed by silica-supported ferric hydrogensulfate

Rahimizadeh, Mohammad; Hosseini, Mirza Hassan; Javadian-Saraf, Aida

doi:10.1007/s00706-012-0800-y

Cited by 17 publications

(8 citation statements)

References 61 publications

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“…Decreasing of reaction times, increasing of isolated yields, low percent of bis indolylmethane formation as byproduct and solvent free conditions are the benefits of this method by means of FHS as catalyst. 29…”

Section: Resultsmentioning

confidence: 99%

One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO₄)₃ as a Recyclable Catalyst

Rahimizadeh

Mokaber-Esfahani

Gholizadeh

2014

J Chinese Chemical Soc

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Solvent-free synthesis of 3-substituted indole derivatives by a one-pot three-component coupling reaction between aldehyde, N-alkyl aniline and indole by Fe(HSO 4 ) 3 catalyzed is described. The noticeable features of this protocol are the simplicity of the procedure, easy synthesized, recyclable and inexpensive catalyst, no organic solvent and high yields in relatively short reaction times. Scheme 1 Catalytic synthesis of 3-aminoalkylated indolescreasing the amount of catalyst from 10 to 5 mol % lowered the substrate conversion rate (Entry 12).Surprisingly, omitting the solvent made the reaction faster and a much better yield of desired indolylmethane

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Section: Resultsmentioning

confidence: 99%

One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO₄)₃ as a Recyclable Catalyst

Rahimizadeh

Mokaber-Esfahani

Gholizadeh

2014

J Chinese Chemical Soc

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“…Elemental analyses were obtained on a Thermo Finnigan Flash EA micro-analyzer. Silica supported ferric hydrogensulfate prepared as we previously reported [19].…”

Section: Generalmentioning

confidence: 99%

Silica supported Fe(HSO4)3 as an efficient, heterogeneous and recyclable catalyst for synthesis of β-enaminones and β-enamino esters

Eshghi

Seyedi

Safaei

et al. 2012

Journal of Molecular Catalysis A: Chemical

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“…The first iron‐salt‐catalyzed three‐component Mannich reaction was reported in 2013 by Eshghi et al . The effect of different iron salts was studied and the authors found that ferric hydrogen sulfate (FHS) was the best salt for this transformation.…”

Section: Classification Based On Catalytic Systemmentioning

confidence: 99%

Recent Developments and Perspectives in the Asymmetric Mannich Reaction

et al. 2018

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The asymmetricM annichr eactioni savery important method for CÀCb ond formation,a nd it is the classical method for the preparation of b-amino ketones and aldehydes. The resulting b-amino carbonyl compounds are widely found in nature, which attests to the importance of this reaction. This Focus Review providesa no verview of asymmetricM annich reactions, the various catalysts that have been used, and its applications,f or papers published since 2013. Scheme1.The Mannich reaction.Scheme2.The mechanism of the Mannich reaction;reproduced with permissionfrom Ref.[1]. andhi University. His research interests are in the areaso fo rganic synthesis, medicinal chemistry,a nd catalysis, in particularr uthenium-, iron-, zinc-, and copper-catalyzedr eactions. His h-index is 24.

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Diastereoselective three-component Mannich reaction catalyzed by silica-supported ferric hydrogensulfate

Cited by 17 publications

References 61 publications

One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO₄)₃ as a Recyclable Catalyst

One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO₄)₃ as a Recyclable Catalyst

Silica supported Fe(HSO4)3 as an efficient, heterogeneous and recyclable catalyst for synthesis of β-enaminones and β-enamino esters

Recent Developments and Perspectives in the Asymmetric Mannich Reaction

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Diastereoselective three-component Mannich reaction catalyzed by silica-supported ferric hydrogensulfate

Cited by 17 publications

References 61 publications

One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO4)3 as a Recyclable Catalyst

One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO4)3 as a Recyclable Catalyst

Silica supported Fe(HSO4)3 as an efficient, heterogeneous and recyclable catalyst for synthesis of β-enaminones and β-enamino esters

Recent Developments and Perspectives in the Asymmetric Mannich Reaction

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One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO₄)₃ as a Recyclable Catalyst

One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO₄)₃ as a Recyclable Catalyst