Diagnostic usefulness of FibroMeter VCTE for hepatic fibrosis in patients with nonalcoholic fatty liver disease

Abstract

Our preliminary findings indicate that FibroMeter VCTE is superior to both NFSA and TE for the diagnosis of severe fibrosis in patients with NAFLD.

Systematic review and meta‐analysis: non‐invasive detection of non‐alcoholic fatty liver disease related fibrosis in the obese

“…Of the serum-based diagnostic tests, we found that complex scores show better accuracy than simple scores. Previous individual studies support these findings in general NAFLD populations (52,53,55). In our meta-analysis, both the NFS and BARD had average, and often poor, pooled sensitivities and specificities, with high heterogeneity.…”

Direct comparison of the specialised blood fibrosis tests FibroMeterV2G and Enhanced Liver Fibrosis score in patients with non‐alcoholic fatty liver disease from tertiary care centres

“…The FibroMeter tests include the FibroMeter VCTE which is a combination of blood markers with the Fibroscan result (Echosens) in a single formula (Table S1 and Table ). Recent studies have demonstrated that the combinatory FibroMeter VCTE outperforms blood fibrosis tests and Fibroscan for the non‐invasive evaluation of liver fibrosis in NAFLD . Used as second‐line procedure after blood fibrosis tests or Fibroscan, the FibroMeter VCTE decreases the rate of patients with undetermined diagnosis by twofold …”

Application of the combined FibroMeter vibration‐controlled transient elastography algorithm in Chinese patients with non‐alcoholic fatty liver disease

“…Another FibroMeter model named FM VCTE has been developed for hepatitis C virus patients by combining clinical and biological parameters together with liver stiffness by transient elastography . In a pilot study of 52 NAFLD patients, FM VCTE detected severe fibrosis with a higher accuracy than transient elastography alone …”

“…16 In a pilot study of 52 NAFLD patients, FM VCTE detected severe fibrosis with a higher accuracy than transient elastography alone. 17 With this background, we aimed to evaluate the diagnostic performance of transient elastography, FM NAFLD, and FM VCTE in fibrosis staging in NAFLD patients and to compare their performances with other scores for fibrosis. We also tested the hypothesis that the use of FM VCTE could resolve diagnostic uncertainties in patients with inconclusive FibroScan results.…”