Diagnostic accuracy of the<scp>R</scp>ivalta test for feline infectious peritonitis

Fischer, Yvonne; Sauter‐Louis, Carola; Hartmann, Katrin

doi:10.1111/j.1939-165x.2012.00464.x

Cited by 48 publications

(49 citation statements)

References 35 publications

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“…A positive Rivalta test was once believed to be highly specific for FIP fluid. In a study of 497 cats with effusions, 35% of which had confirmed FIP, the Rivalta test had a sensitivity of 91% and a specificity of 66%, with a positive predictive value of 58% and a negative predictive value of 93% (Fischer et al, 2012). As would be expected, these values increased when cats with lymphosarcoma or bacterial infections were excluded, or when only cats of ≥2 years of age were considered.…”

Section: Rivalta Testmentioning

confidence: 81%

An update on feline infectious peritonitis: Diagnostics and therapeutics

Pedersen

2014

The Veterinary Journal

167

252

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This review is concerned with what has been learned about feline infectious peritonitis (FIP) diagnostics and therapeutics since the publication of an extensive overview of literature covering the period 1963-2009. Although progress has been made in both areas, obtaining a definitive diagnosis of FIP remains a problem for those veterinarians and/or cat owners who require absolute certainty. This review will cover both indirect and direct diagnostic tests for the disease and will emphasize their limitations, as well as their specificity and sensitivity. There is still no effective treatment for FIP, although there are both claims that such therapies exist and glimmers of hope coming from new therapies that are under research. FIP has also been identified in wild felids and FIP-like disease is now a growing problem among pet ferrets.

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Section: Rivalta Testmentioning

confidence: 81%

An update on feline infectious peritonitis: Diagnostics and therapeutics

Pedersen

2014

The Veterinary Journal

167

252

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“…Slowly layer one drop of the effusion fluid to the surface of the acetic acid solution. The sensitivity and specificity of the Rivalta test are reported to be 91.3% and 65.5%, respectively (Fischer et al, 2012). 6-14C).…”

Section: Feline Infectious Peritonitismentioning

confidence: 97%

“…To perform this relatively simple test, place one drop of 98% acetic acid into 5-mL distilled water and mix well in a clear reagent tube. This test has a recently reported PPV of 58.4% to 88.4% and NPV of 66.7% to 93.4% (Fischer et al, 2012) in contrast to PPV of 86% and NPV of 97% in an earlier study (Hartmann et al, 2003). A positive test requires that the drop of effusion retain its form on the surface or slowly sink to the bottom as a droplet or jellyfish-like shape ( Fig.…”

Section: Feline Infectious Peritonitismentioning

confidence: 98%

“…Feline infectious peritonitis (FIP) is unique among the causes of inflammatory effusion in that the fluid that accumulates is usually high in protein, yet it has a relatively low cellularity (Fischer et al, 2012;McReynolds and Macy, 1997;Norris et al, 2005). FIP has been noted to cause 18% of pleural (Davies and Forrester, 1996), 9.8% of pericardial (Davidson et al, 2008), and 5% of abdominal (Wright, 1999) effusions.…”

Section: Feline Infectious Peritonitismentioning

confidence: 99%

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Body Cavity Fluids

Thompson¹,

Rebar²

2016

Canine and Feline Cytology

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“…1,2 Traditionally, the specimens of ascites are classified into broad categories of transudates or exudates according to AFTP concentration. 6,7 Samples are categorized as transudates, if the AFTP is less than 25 g/L and as exudates if AFTP is greater than 25 g/L. Exudative ascites caused by an inflammatory or malignant tumor is high in protein; transudative ascites caused by cirrhosis, heart failure, and nephrotic syndrome is low in protein due to an imbalance of Starling forces.…”

Section: Introductionmentioning

confidence: 99%

Ascitic fluid total protein, a useful marker in non‐portal hypertensive ascites

Zhu

et al. 2019

J of Gastro and Hepatol

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Background and Aims Diagnostic performance of ascitic fluid total protein (AFTP) concentration remained unsettled. Our aim was to determine diagnostic value of AFTP in differential diagnosis of causes of ascites. Methods Seven hundred four consecutive patients with new‐onset ascites were prospectively enrolled in this study. Results In the training cohort, diagnostic performance of quantitative AFTP assay was superior to that of Rivalta test in differential diagnosis of ascites. At the predetermined cut‐off value of 25 g/L, quantitative AFTP assay was more useful in the differentiation of non‐portal hypertensive ascites from portal hypertensive ascites compared with the exudate–transudate classification, area under curve of receiver operating characteristic curve was 0.958. Quantitative AFTP assay was superior to serum–ascites albumin gradient in the detection of non‐portal hypertensive ascites, especially malignant ascites and tuberculous peritonitis. In mixed ascites, AFTP was useful in identifying peritoneal lesions. Conclusions Ascitic fluid total protein is a useful marker in non‐portal hypertensive ascites; thus, it should be determined in diagnostic work‐up of the patients with ascites.

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Diagnostic accuracy of theRivalta test for feline infectious peritonitis

Cited by 48 publications

References 35 publications

An update on feline infectious peritonitis: Diagnostics and therapeutics

An update on feline infectious peritonitis: Diagnostics and therapeutics

Body Cavity Fluids

Ascitic fluid total protein, a useful marker in non‐portal hypertensive ascites

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