Diagnosis of upper urinary tract tumours: Is photodynamic diagnosis assisted ureterorenoscopy required as an addition to modern imaging and ureterorenoscopy?

Aboumarzouk, Omar; Mains, Edward; Moseley, Harry; Kata, S.G.

doi:10.1016/j.pdpdt.2012.11.008

Cited by 30 publications

(30 citation statements)

References 24 publications

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“…19 In two larger studies, more lesions were found in the upper urinary tract compared with standard white-light imaging. 20,21 Although a study on sensitivity and specificity of UUT-PDD revealed an increased sensitivity compared with standard white-light endoscopy, this difference was not statistically significant. 20,21 In summary, PDD enables improved visualization of upper urinary tract tumors.…”

Section: Techniques Based On Fluorescencementioning

confidence: 96%

Optical Diagnostics for Upper Urinary Tract Urothelial Cancer: Technology, Thresholds, and Clinical Applications

Bus

Bruin

Faber

et al. 2015

Journal of Endourology

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NBI, SPIES, and PDD aim at improving visualization of UUT-UC through contrast enhancement. OCT and CLE aim at providing real-time predictions of histopathological diagnosis. For all techniques, more research has to be conducted before these techniques can be implemented in the routine management of UUT-UC. All techniques might be of value in specific clinical scenarios and allow for integration, for example, OCT with NBI, and could therefore improve tumor detection and staging and help in selecting the optimal treatment for the individual patient.

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Section: Techniques Based On Fluorescencementioning

confidence: 96%

Optical Diagnostics for Upper Urinary Tract Urothelial Cancer: Technology, Thresholds, and Clinical Applications

Bus

Bruin

Faber

et al. 2015

Journal of Endourology

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“…This was clinically significant as 13% of patients with cancer were missed completely by white light ureteroscopy and only detected by blue light. Furthermore, we found that blue light detected more lesions than CT scans, which missed nearly 18% of lesions [8]. …”

Section: Our Experience To Datementioning

confidence: 99%

“…Regardless of suggested differences between the upper and lower urinary tract, we have found photodynamic diagnosis to be of great value in increasing detection rates in the UUT as well, especially for flat lesions [5,7,8]. …”

Section: Introductionmentioning

confidence: 99%

Photodynamic Diagnostic Ureterorenoscopy with Orally Administered 5-Aminolaevulinic Acid as Photosensitiser: How I Do It

Kata

Nabi²,

Eljamel³

et al. 2014

Urol Int

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Objective: To explain our use of photodynamic diagnostic ureterorenoscopy, we provide a detailed description of the choice of photosensitiser, equipment needed, a safety profile, and pointers on our technique. Technique: Patients are given oral 5-aminolaevulinic acid (5-ALA) as a photosensitiser 3-4 h pre-operatively, and by using a Xenon blue light source, an eyepiece which blocks light below 450 nm which is fitted onto the ureterorenoscope, we are able to conduct a thorough photodiagnosis of the upper urinary tract. Conclusion: Our technique of photodynamic diagnostic ureterorenoscopy has shown that the sensitivity, specificity and detection rates of upper urinary tract lesions can be significantly increased with the use of oral 5-ALA. Therefore, we provide a detailed explanation of the use of oral 5-ALA photosensitiser, indications and contraindications of the technique in addition to equipment used and potential complications of the procedures.

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“…Sur le plan pratique, l'instillation du produit dans la VES pose problème et le temps de contact avec l'urothélium est limité car il ne s'agit pas d'un organe de stockage, contrairement à la vessie. Il semblerait néanmoins que l'utilisation du PDD puisse améliorer le taux de détection global et de lésion de CIS [24,25].…”

Section: L'urétérorénoscopie Souple (Urss)unclassified

Diagnostics clinique, urétéroscopique et photodynamique des tumeurs de la voie excrétrice urinaire supérieures : état-de-l’art pour le rapport scientifique annuel de l’Association française d’urologie

Nison¹,

Bozzini²,

Rouprêt³

et al. 2014

Progrès en Urologie

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Diagnosis of upper urinary tract tumours: Is photodynamic diagnosis assisted ureterorenoscopy required as an addition to modern imaging and ureterorenoscopy?

Cited by 30 publications

References 24 publications

Optical Diagnostics for Upper Urinary Tract Urothelial Cancer: Technology, Thresholds, and Clinical Applications

Optical Diagnostics for Upper Urinary Tract Urothelial Cancer: Technology, Thresholds, and Clinical Applications

Photodynamic Diagnostic Ureterorenoscopy with Orally Administered 5-Aminolaevulinic Acid as Photosensitiser: How I Do It

Diagnostics clinique, urétéroscopique et photodynamique des tumeurs de la voie excrétrice urinaire supérieures : état-de-l’art pour le rapport scientifique annuel de l’Association française d’urologie

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