Diagnosis and Treatment of Allergic Rhinitis due to House-Dust Mites in Spain

Valero, Antonio; Justicia, José L; Vidal, Carmen; Rodríguez, Virginia; Muñoz, Rosa Garcia; Garcia, Mario

doi:10.2500/ajra.2012.26.3695

Cited by 7 publications

(10 citation statements)

References 30 publications

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“…The treatment profile for HDM-allergic patients also differed, with significantly greater used of topical corticosteroids. The average number of co-prescriptions was 2.1, and around 9 % of the patients had received a prescription for AIT [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

“A year-long, fortnightly, observational survey in three European countries of patients with respiratory allergies induced by house dust mites: Methodology, demographics and clinical characteristics”

et al. 2016

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BackgroundHouse dust mite (HDM) allergens constitute the leading trigger for the symptoms of persistent respiratory allergies (such as allergic rhinitis and asthma). However, the fluctuating, pernicious nature of the symptoms has given rise to a perception that HDM-induced respiratory allergy is not a “real” disease.MethodsIn order to assess the self-reported disease profile and behaviour of adult patients with a self-reported history of severe, poorly controlled, physician-diagnosed HDM respiratory allergy, we performed an observational, international, multicentre survey in three European countries (France, Italy and Spain). Participants were included in the survey if they passed a short Internet-based screening questionnaire. Following completion of a detailed post-inclusion questionnaire, 28 fortnightly telephone interviews were used to gather extensive data on the participants’ symptom prevalence and intensity, medical consultations, disease burden, quality of life, and medication use from late May 2012 to early July 2013.ResultsTwenty-two thousand nine hundred ninety five individuals completed the Internet screening questionnaire and 339 respondents (67 % female) met all the inclusion criteria. 313 of the 339 (92 %) completed the post-inclusion questionnaire (n = 114 in Italy, 92 in France and 107 in Spain). The median time since the first symptoms of HDM allergy was over 13 years in all three countries. The response rate for the fortnightly interviews averaged 75 % (range: 29 to 97 %). The reported fortnightly prevalence of nasal and ocular symptoms peaked in the autumn (September to November) and spring (March to May). These peaks in prevalence coincided with increased reports of symptom worsening and higher physician consultation rates. In participants not allergic to pollen, the autumn and spring peaks were accompanied by a third peak in late December 2012. Very few participants reported that their symptoms had never improved (4 %) or never worsened (11 %) during the survey period.ConclusionsIn a survey in France, Italy and Spain, patients with severe HDM-induced respiratory allergies experienced a complex set of changing, troublesome symptoms throughout the year, with peaks in spring, autumn and (to a lesser extent) mid-winter.Electronic supplementary materialThe online version of this article (doi:10.1186/s12890-016-0246-9) contains supplementary material, which is available to authorized users.

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Section: Introductionmentioning

confidence: 99%

“A year-long, fortnightly, observational survey in three European countries of patients with respiratory allergies induced by house dust mites: Methodology, demographics and clinical characteristics”

et al. 2016

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“…investigated AR patients, specifically sensitized to HDM, seen by specialists and found 70% of PER AR. 20 Compared with Valero et al . our findings were different because PER AR frequency in our HDM-sensitized subjects (see Table 3) was not higher than the country's mean.…”

Section: Discussionmentioning

confidence: 93%

“…The prevalence of rhinitis phenotypes has been studied by several other investigators over the last 10 years, in Europe (Spain, 18–20 Italy, 21 France, 22 Poland, 23 Bulgaria, 24 and Greece 25 ) and in the Middle 26 and Far East (Malaysia 27 and China 28,29 ). In one-half of the reports INT is more frequent, in the other half PER prevails, varying from 26 29 to 73%, 30 according to the country, data collection method applied and the type of patient studied: from telephone interviews to the public at large on one hand, to confirmed AR patients seen by specialists on the other.…”

Section: Discussionmentioning

confidence: 99%

In the (Sub)Tropics Allergic Rhinitis and Its Impact on Asthma Classification of Allergic Rhinitis is More Useful than Perennial–Seasonal Classification

Larenas‐Linnemann

Michels

Dinger

et al. 2014

Am J Rhinol�Allergy

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“…18 In a recent Spanish survey, just 15% of allergic rhinitis patients sensitized to dust mites reported an improvement after pharmacological treatment. 19 Another possibility would be that patients with perennial allergic rhinitis do not take adequate treatment due to an effective allergen avoidance. A recent update of the Cochrane Review on house dust mites avoidance and allergic rhinitis stated that dust mites impermeable bedding and other preventive measures are not proven to give a substantial benefit to control rhinitis symptoms.…”

Section: Main Findingsmentioning

confidence: 99%

Characteristics and predictors of allergic rhinitis undertreatment in primary care

Spinozzi

Murgia

Baldacci

et al. 2015

Int J Immunopathol Pharmacol

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Although allergic rhinitis is considered a raising medical problem in many countries it is often undertreated. The reasons for this phenomenon are not completely clear.The aim of this study is to evaluate factors associated with allergic rhinitis under-/no treatment. A sample of 518 allergic rhinitis patients recruited by their primary care physicians, as a part of the ARGA study, were invited to fill in a specific questionnaire regarding rhinitis symptoms, treatment, and rhinitis-related work/social disability. Chi-square test and logistic regression were performed to assess risk factors for allergic rhinitis under-/no treatment.Over one out of four patients had no treatment despite the symptoms and 13.5% were inadequately treated. Participants with asthma (OR 0.47, 95% CI 0.30-0.75) and conjunctivitis (0.44, 95% CI 0.27-0.71) were at lower risk of allergic rhinitis under-/no treatment: in asthmatics this reduction was related mainly to the concomitant asthma treatment (OR 0.19, 95% CI 0.10-0.37).Asthmatics with under-/not treated rhinitis had the highest prevalence of rhinitis-related quality of life impairment. Under-/no treatment for allergic rhinitis is still rather frequent despite the relevance of this disease. The simultaneous presence of asthma and an anti-asthmatic therapy are able to influence positively the treatment. Targeted interventions toward a better characterization and a tight follow-up of rhinitis patient without asthma are needed.

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Diagnosis and Treatment of Allergic Rhinitis due to House-Dust Mites in Spain

Cited by 7 publications

References 30 publications

“A year-long, fortnightly, observational survey in three European countries of patients with respiratory allergies induced by house dust mites: Methodology, demographics and clinical characteristics”

“A year-long, fortnightly, observational survey in three European countries of patients with respiratory allergies induced by house dust mites: Methodology, demographics and clinical characteristics”

In the (Sub)Tropics Allergic Rhinitis and Its Impact on Asthma Classification of Allergic Rhinitis is More Useful than Perennial–Seasonal Classification

Characteristics and predictors of allergic rhinitis undertreatment in primary care

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