Diagnosis and successful treatment of diarrhoea in horses caused by immature small strongyles apparently insusceptible to anthelmintics

Recurrent diarrhoea in aged ponies associated with larval cyathostomiasis

“…Of 15 cases reported by Giles et al (1985), only 3 were aged over 10 years (2 aged 12 and 1 aged 16 years). Most of the other recorded cases of the condition have also been in the 1-5 years of age range (Blackwell 1973;Chiejina and Mason 1977;Jeggo andSewell 1977: Jasko andRoth 1984;Church et al 1986;Harmon et al 1986). The recurrent nature of the disease observed here has not been described before.…”

Equine parasite control ‐ Problems associated with intensive anthelmintic therapy

“…Horses with 'larval cyathostomiasis' pose a special problem because anthelmintic treatment is likely to be of benefit only after larvae emerge from their refuge and the damage is done. Horses with severe clinical signs of 'larval cyathostomiasis' have shown variable clinical responses to ivermectin, or to fenbendazole at repeated elevated dosages (Jeggo and Sewell 1977;Giles, Urquhart and Longstaffe 1985;Church, Kelly and Obwolo 1986). In two clinical cases where there was no response to ivermectin or fenbendazole at various dosages, a course of dexamethasone to suppress the inflammatory response to emerging cyathostome larvae resulted in marked clinical improvement (Church et al 1986).…”

Diagnostic and prognostic value of serum protein electrophoresis in horses with chronic diarrhoea

“…Both of these findings confirm that diarrhoea1 diseases associated with severe inflammatory changes in the intestinal wall are associated with the highest mortality rates. Anti-inflammatory agents are useful in the treatment of diseases such as larval cyathostomiasis (Church et al 1986). Significantly higher levels of beta-1-globulin were found in horses with.…”