Diagnosis and Management of Atopic Dermatitis: A Review

Abstract

Atopic dermatitis is a chronic, relapsing, intensely pruritic inflammatory skin disease that affects both children and adults. This article provides an overview of the epidemiology, clinical features, pathophysiology, complications, and specific investigations of atopic dermatitis. The current and novel therapies for the treatment of atopic dermatitis will be discussed. GENERAL PURPOSE: The purpose of this learning activity is to provide information about the diagnosis and management of atopic dermatitis (AD). TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After completing this continuing education activity, you should be able to: 1. Recall the diagnostic process of AD. 2. Identify nonpharmacologic therapies for skin care in patients with AD. 3. Explain the pharmacologic management of AD.

Atopic Dermatitis and Comorbidity

“…The topical use of antihistamines in the treatment of atopic dermatitis is not recommended. Some patients benefit from phototherapy, and UV light can reduce the symptoms of pruritus [43,[46][47][48].…”

Anti‐atopic dermatitis effects of hydrolyzed celery extract in mice

“…AD foretells the onset of immunoglobulin E (IgE)‐mediated allergic diseases like asthma, allergic rhinitis, and food sensitivities (Jansen, Haapalahti, & Hopsu‐Havu, 1973). The decreased skin barrier also facilitates the overgrowth of microorganisms like bacteria, viruses, and yeast, often presenting the crust skin and secondary impetigo (Maliyar, Sibbald, Pope, & Gary Sibbald, 2018). Although the pathogenesis of AD is thought to be complex or even unknown, most researchers hold that immune dysfunction and epidermal barrier distortion leads to IgE sensitization that constitutes critical factors in cutaneous inflammation.…”

Modern Outlooks on «Atopic March» Secondary Prevention Capabilities in Children with Atopic Dermatitis

“…CURRENT PEDIATRICS / 2020 / V. 19 / № 4S АТОПИЧЕСКИЙ ДЕРМАТИТ -ИСХОДНАЯ ТОЧКА РАЗВИТИЯ «АТОПИЧЕСКОГО МАРША» Атопический дерматит (АтД) является многофакторным хроническим рецидивирующим воспалительным заболеванием кожи, поражающим как детей, так и взрослых, а также оказывающим огромное негативное влияние на качество жизни больных [1]. Наиболее подвержены заболеванию дети раннего возраста: до 50% всех случаев дебюта АтД регистрируют у детей первого года жизни, до 85% -в возрасте до 5 лет [2].…”