Diabetic Dermangiopathy.

Abstract

SUMMARY Necrobiosis Lipoidica Diabeticorum (NLD) and Pigmented Pretibial Patches (PPP) are characterized by their association with diabetes mellitus, by their pretibial predilection, and by vascular alterations compatible with diabetic microangiopathy. Despite differences in the gross and microscopic morphology, both may be considered part of a spectrum of cutaneous lesions for which the term diabetic dermangiopathy is suggested. Variants within this spectrum are reported, including 2 cases with widespread lesions of PPP, occurring in areas other than pretibial.

Necrobiosis Lipoidica Diabeticorum

“…Bauer & Levan (1970) reported two cases of extra-pretibial diabetic dermopathy assoeiated wifh NLD and suggested that diabetic dermopathy may be the precursor of NLD. The hyperpigmented macules of "diabetic dermopathy" sometimes coexist with NLD on the anterior shins.…”

Diabetes mellitus and the skin

“… 85 The plaques result from the confluence of yellowish papules and often develop atrophic center that corresponds to the dermal and epidermal atrophy associated with superficial telangiectasias. 86 …”

Cutaneous Manifestations of Diabetes Mellitus in Children

“…Although many workers believe that the lesions are significantly related to the occurrence of diabetic macroangiopathic complications (26,54), shin spots may precede the appearance of glucose intolerance {1! 8), and even appear in a small number of individuals who maintain normal glucose tolerance over the subsequent years (118).…”

“…It has been suggested that NLD, GA, diabetic dermopathy, and bullosis diabeticorum be classified as diabetic dermangiopathies to emphasize the similarity between the microvascular changes in these four diseases and in the microangiopathic changes in other organ systems observed in diabetic patients (118).…”