Diabetes and Hypertension: Is There a Common Metabolic Pathway?

Cheung, Bmy; Li, Chao

doi:10.1007/s11883-012-0227-2

Cited by 454 publications

(362 citation statements)

References 110 publications

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“…The association obesity and high BP is well documented in the literature. 17,[25][26][27] Despite the well-documented association between diabetes and hypertension in literature, diabetes was not found to be associated with hypertension in this particular study. This may be attributed, in part, to the low prevalence of diabetes among participants; a fact that in turn be explained by the significant physical activity observed in individuals of this tribe.…”

mentioning

confidence: 84%

High prevalence of hypertension among an ethnic group in Sudan: implications for prevention

et al. 2016

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Objective Hypertension is an emerging non-communicable disease in developing countries. Due to its silent nature and serious complications, active screening is essential in order to prevent complications. For instance, premature mortality from cardiovascular diseases could be prevented by the effective control of hypertension. The aim of this study was to determine the prevalence of undiagnosed hypertension among Nuba ethnic group living in Atbara city, north Sudan and to identify the associated risk factors. Subject and methods All consenting 500 adults from Nuba tribe who live in El Wihda District, Atbara were included. Blood pressure (BP) and body mass index were measured. Standard interviewing procedures were used to record medical history, sociodemographic data, and lifestyle characteristics. Results Among the 500 participants, females were 364 (72.8%) and males were 136 (27.2%). The overall prevalence of undiagnosed hypertension was 49.4% (30.8% stage 1 hypertension and 18.6% stage 2 hypertension). In addition, 41% of the population was having prehypertension. The significant risk factors for high BP were: male sex, age above 45 years, overweight, illiteracy, and alcohol consumption. Conclusion Undiagnosed high BP is very common among Nuba ethnic group; therefore, active screening and early management are recommended to prevent complications. ARTICLE HISTORY

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confidence: 84%

High prevalence of hypertension among an ethnic group in Sudan: implications for prevention

et al. 2016

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“…Hypertension alone is considered as the risk factor for many cardiovascular diseases, including new onset of diabetes. Many studies found a close association of essential hypertension with diabetes mellitus as both share a common metabolic pathway and also both affect the pathophysiology of one another [5,6]. Around one-third hypertensive patients are reported to develop diabetes in later stages of hypertension [7].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors of Essential Hypertension and New Onset of Diabetes in Essential Hypertension in Rural Population of Haryana

Jhawat¹,

Gupta²,

Agarwal

et al. 2018

Int J Pharm Pharm Sci

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Objective: We conducted a well-designed prevalence study in a rural population of Haryana in Mullana rural area to find out the latest prevalence of essential hypertension, the prescription pattern of antihypertensive drugs and the associated risk of new onset of diabetes. Methods:A retrospective study was carried out on the patient data (2672 patients) from the years 2009 to 2013 at OPD of M. M. University hospital, Mullana to find the previous year's prevalence of different diseases, including essential hypertension, new onset of diabetes and associated risk factors, prescription pattern of antihypertensive drug therapy. Based on the above results, a prospective study was conducted from January 2015 to December 2016 and total 510 patients (270 essential hypertension and 240 essential hypertension with new onset of diabetes) and 270 normal individuals were recruited in the study. Results:The retrospective study, a total of 2672 patients' data was evaluated which showed 41.21% prevalence of essential hypertension, 11.83% new onset of diabetes in Essential hypertension patients and 15.87% diabetic patients. Antihypertensive monotherapy was prescribed to 59.85% patients and combination therapy to 40.15% patients while that of a prospective study showed 40.37% patients of monotherapy and 59.63% patients of combination therapy. The prospective study also showed that different anthropometric parameters were significantly associated with risk of hypertension and new onset of diabetes except for age and height. Conclusion:An increase in the prevalence of essential hypertension and associated risk factors was observed when compared with previous studies and retrospective study. It is clearly seen by the change in drug therapy pattern and different anthropometric parameters. Implementation of a large scale awareness program is needed to combat these metabolic diseases.

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“…These pathways interact, influence each other and can even cause a vicious cycle. SAH and diabetes are the two final results of the metabolic syndrome and as a consequence, may develop one after another in the same individual (34) . The increased survival rate resulting from ART has been achieved at the expense of high incidence of unforeseen adverse metabolic effects, including insulin resistance, diabetes, dyslipidemia and lipodystrophy (35) .…”

Section: Discussionmentioning

confidence: 99%

Systemic Arterial Hypertension in people living with HIV/AIDS: integrative review

et al. 2017

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Objective: To analyze scientific productions about the relationship between HIV and Systemic Arterial Hypertension (SAH) in people living with HIV/AIDS (PLWHA). Method: Integrative literature review in six databases, held in March 2016. “AIDS” and “hypertension” were the keywords used in Portuguese, English and Spanish languages. We found 248 articles and selected 17. The categories formulated were “prevalence of SAH in PLWHA,” “risk factors for SAH in PLWHA” and “adverse events of antiretroviral therapy (ART) that contribute to HAS.” Results: There is no consensus whether HIV and ART influence the SAH development, but there are several risk factors for SAH among PLWHA. It was observed that protease inhibitors medicines influence SAH the most. Conclusion: Guidelines for SAH prevention must be performed in all individuals, however, in PLWHA, they must focus on characteristic risk factors of this population.

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Diabetes and Hypertension: Is There a Common Metabolic Pathway?

Cited by 454 publications

References 110 publications

High prevalence of hypertension among an ethnic group in Sudan: implications for prevention

High prevalence of hypertension among an ethnic group in Sudan: implications for prevention

Prevalence and Risk Factors of Essential Hypertension and New Onset of Diabetes in Essential Hypertension in Rural Population of Haryana

Systemic Arterial Hypertension in people living with HIV/AIDS: integrative review

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