Systemic Arterial Hypertension in people living with HIV/AIDS: integrative review

Lima, Maria Amanda Correia; Cunha, Gilmara Holanda da; Galvão, Marli Teresinha Gimeniz; Rocha, Ryvanne Paulino; Franco, Kátia Barbosa; Fontenele, Marina Soares Monteiro

doi:10.1590/0034-7167-2016-0416

Cited by 8 publications

(4 citation statements)

References 29 publications

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“…Some studies have linked protease inhibitors to greater risk of CVD and complications, specifically cholesterol, obesity, lipid levels, and diabetes, whereas others have found no association . In this analysis, protease inhibitors were not significantly associated with HTN even though 16% (63/397) of patients were on protease inhibitor regimens at the time of CVDRF screening compared to only 1% (3/397) at time of ART initiation.…”

Section: Discussionmentioning

confidence: 54%

Prevalence of hypertension and cardiovascular risk factors among long‐term AIDS survivors: A report from the field

Pierre

Seo

Rivera

et al. 2019

J of Clinical Hypertension

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HIV infection is associated with increased risk and progression of cardiovascular disease (CVD), yet little is known about the prevalence of CVD risk factors among long‐term AIDS survivors in resource‐limited settings. Using routinely collected data, we conducted a retrospective study to describe the prevalence of CVD risk factors among a cohort of HIV‐infected patients followed for over 10 years in Port‐au Prince, Haiti. This cohort includes 910 adults who initiated antiretroviral therapy (ART) between 2003 and 2004 and remained in care between 2014 and 2016 when routine screening for CVD risk factors was implemented at a large clinic in Haiti. A total of 397 remained in care ≥10 years and received screening. At ART initiation, 59% were female, median age was 38 years (IQR 33‐44), and median CD4 count was 117 cells/mm3 (IQR 34‐201). Median follow‐up time from ART initiation was 12.1 years (IQR 11.7‐12.7). At screening, median CD4 count was 574 cells/mm3 (IQR 378‐771), and 84% (282 of 336 screened) had HIV‐1 RNA < 1000 copies/mL. Seventy‐four percent of patients had at least 1 risk factor including 58% (224/385) with hypertension, 8% (24/297) diabetes, 43% (119/275) hypercholesterolemia, 8% (20/248) active smoking, and 10% (25/245) obesity. Factors associated with hypertension were age (adjusted OR 1.06, P < .001) and weight at screening (adjusted OR 1.02, P = .019). Long‐term AIDS survivors have a high prevalence of CVD risk factors, primarily hypertension. Integration of cardiovascular screening and management into routine HIV care is needed to maximize health outcomes among aging HIV patients in resource‐limited settings.

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Section: Discussionmentioning

confidence: 54%

Prevalence of hypertension and cardiovascular risk factors among long‐term AIDS survivors: A report from the field

Pierre

Seo

Rivera

et al. 2019

J of Clinical Hypertension

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“…(16) Sabe-se que o avançar da idade, por si só, aumenta o risco para doenças crônicas não transmissíveis, dentre elas as cardiovasculares, tornando claro a importância de atuar sobre os fatores modificáveis, de modo a reduzir os riscos e melhorar a qualidade de vida desta população. (17) Além disso, neste estudo foi identificada associação entre os antecedentes familiares para HAS (p=0,026), DM (p=0,003), IAM (p=0,004) e AVE (p=0,003) para com o risco cardiovascular, confirmando a evidência da relação entre hereditariedade e as DCV. Tais dados corroboram com um estudo realizado na China, o qual evidenciou que no grupo de PVHA as variáveis idade avançada, excesso de peso e história familiar de doenças cardiovasculares também foram associados ao maior risco cardiovascular.…”

Section: Imetodologiaunclassified

Associação Entre Hábitos De Vida E Risco Cardiovascular Em Pessoas Vivendo Com Hiv/Aids

et al. 2018

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Objetivo: analisar os hábitos de vida e o risco cardiovascular de pessoas vivendo com o vírus da imunodeficiênciahumana, por meio de fatores sociodemográficos, clínicos e comportamentais. Método: trata-se de estudo transversal,quantitativo, realizado em serviços especializados no atendimento de pessoas vivendo com o vírus da imunodeficiênciahumana, no período de 2014 a 2016, num município no interior do estado de São Paulo – Brasil. Utilizou-se Escorede Risco de Framingham para estratificação do risco cardiovascular. Resultados: participaram 340 pessoas. Houveassociação entre o risco cardiovascular e as variáveis sexo (p=0,003), idade (p<0,001), escolaridade (p=0,006), antecedentesfamiliares para Hipertensão (p=0,026), Diabetes (p=0,003), Infarto do Miocárdio (p=0,004) e Acidente VascularEncefálico (p=0,003), o tempo de diagnóstico pelo HIV (p<0,001) e uso de antirretrovirais (p=0,003). Conclusão: osresultados apontaram associações entre o risco cardiovascular e os fatores de risco modificáveis e não modificáveis paraocorrência de doenças cardiovasculares em pessoas vivendo com HIV.

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“…Increasing rates of obesity [2] and factors such as smoking and mental health conditions contribute to chronic inflammation among PLWH and likely exacerbate hypertension [3][4][5][6][7]. The negative impact of smoking among PLWH may also exacerbate the already higher risk of hypertension associated with HIV [8,9]. Depression globally affects 31% of PLWH and is a well-established risk factor for hypertension [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Syndemic burden and systemic inflammation, HIV health status, and blood pressure among women with unsuppressed HIV viral loads among women living with HIV

Jones

Rodriguez

Alcaide

et al. 2020

Aids

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Introduction.-Smoking, low education, obesity, and depressive symptoms are all associated with HIV health status, increased blood pressure, and inflammation, and constitute a syndemic burden that may contribute to poor health outcomes. The current study examined syndemic burden and health outcomes among women living with HIV (WLHIV).Methods.-Women were participants enrolled in the Women's Interagency HIV Study (WIHS). Outcomes included blood pressure, HIV health status (HIV-1 RNA viral load and CD4 T-cell counts), and interleukin-6. Syndemic burden was defined as a count variable of low education, obesity, cigarette use, and depressive symptoms.

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Systemic Arterial Hypertension in people living with HIV/AIDS: integrative review

Cited by 8 publications

References 29 publications

Prevalence of hypertension and cardiovascular risk factors among long‐term AIDS survivors: A report from the field

Prevalence of hypertension and cardiovascular risk factors among long‐term AIDS survivors: A report from the field

Associação Entre Hábitos De Vida E Risco Cardiovascular Em Pessoas Vivendo Com Hiv/Aids

Syndemic burden and systemic inflammation, HIV health status, and blood pressure among women with unsuppressed HIV viral loads among women living with HIV

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