The article, thereby, aims to contribute to the burgeoning research strand on new path creation by bringing the debate a step closer to the major point of concern, regional economic development.We demonstrate the use of the framework to understand how new path creation may affect existing economic activities and how this relates to the overall goal of promoting regional economic development in an illustrative case study of the Zambezi region in northeastern Namibia. The Zambezi region, as we will show, is a suitable example to study the effects of new path creation on existing economic structures. Historically, the region relied on agriculture as the main livelihood activity. Since the 1990s, different resource formation processes have contributed to the creation of a tourism path. We analyze this formation process of the tourism path and its influence on the existing agricultural path. The findings highlight that new path development cannot be interpreted as a growth path for the entire region. The formation of the tourism path has generated variegated outcomes within the region, with benefits and losses unevenly distributed among firms and people.