Development of an Electrochemical Sensor Based on Reduced Graphene Oxide Modified Screen‐Printed Carbon Electrode for the Determination of Buprenorphine

Fakhari, Ali Reza; Sahragard, Ali; Ahmar, Hamid

doi:10.1002/elan.201400196

Cited by 24 publications

(11 citation statements)

References 42 publications

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“…GO can differentiate between the voltammograms of the drugs due to their high electrochemical conductivity and sensitivity allowing simultaneous detection (de Araujo et al, 2018 ; Panwar et al, 2019 ; Rawtani et al, 2019 ). The outstanding electrical properties of graphene can be restored by reduction via different methods such as thermal, chemical or electrical strategies that result in a material with a high amount of C-O bonds known as reduced GO (RGO) (Fakhari et al, 2014 ).…”

Section: Nanomaterials For Sensors Design For the Detection Of Drugs mentioning

confidence: 99%

Tackling the Problem of Sensing Commonly Abused Drugs Through Nanomaterials and (Bio)Recognition Approaches

et al. 2020

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We summarize herein the literature in the last decade, involving the use of nanomaterials and various (bio)recognition elements, such as antibodies, aptamers and molecularly imprinted polymers, for the development of sensitive and selective (bio)sensors for illicit drugs with a focus on electrochemical transduction systems. The use and abuse of illicit drugs remains an increasing challenge for worldwide authorities and, therefore, it is important to have accurate methods to detect them in seized samples, biological fluids and wastewaters. They are recently classified as the latest group of “emerging pollutants,” as their consumption has increased tremendously in recent years. Nanomaterials, antibodies, aptamers and molecularly imprinted polymers have gained much attention over the last decade in the development of (bio)sensors for a myriad of applications. The applicability of these (nano)materials, functionalized or not, has significantly increased, and are therefore highly suitable for use in the detection of drugs. Lately, such functionalized nanoscale materials have assisted in the detection of illicit drugs fingerprints, providing large surface area, functional groups and unique properties that facilitate sensitive and selective sensing. The review discusses the types of commonly abused drugs and their toxicological implications, classification of functionalized nanomaterials (graphene, carbon nanotubes), their fabrication, and their application on real samples in different fields of forensic science. Biosensors for drugs of abuse from the last decade's literature are then exemplified. It also offers insights into the prospects and challenges of bringing the functionalized nanobased technology to the end user in the laboratories or in-field.

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Section: Nanomaterials For Sensors Design For the Detection Of Drugs mentioning

confidence: 99%

Tackling the Problem of Sensing Commonly Abused Drugs Through Nanomaterials and (Bio)Recognition Approaches

et al. 2020

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“…21 For example, the amount of GPO used in this work is similar to that of reduced GPO, a material being 4 orders of magnitude higher in conductivity than GPO, 24 employed by Fakhari et al to fabricate SPCE for detecting Buprenorphine. 25 …”

Section: Determination Of Optimum Gpo Concentrationmentioning

confidence: 99%

A Sensitive and Disposable Graphene Oxide Electrochemical Immunosensor for Label-free Detection of Human Immunoglobulin G

Jumpathong

Jakmunee

2016

ANAL. SCI.

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In this work, a cost-effective and simple-to-prepare label-free electrochemical immunosensor was, for the first time, fabricated by modifying high-quality graphene oxide (GPO) onto a screen-printed carbon electrode (SPCE). The anti-IgG antibody was then covalently immobilized to the carboxylic group anchoring on the surface of GPO particles. Under the optimized condition, our newly developed immunosensor selectively bound to human immunoglobulin G (IgG), a model biomarker, with high sensitivity at a limit of detection of 1.99 ng mL -1 , potentially sensitive enough for IgG detection at the pathophysiological level, and had a linear range of 2.5 to 100 ng mL -1 . The proposed immunosensor also exhibited high reproducibility and regenerability, resulting in no significant change in electrochemical signals from different replicates of the electrode, and a robust electrochemical current after being subjected to alkaline base washing with several cycles. To this end, our immunosensor demonstrates ability as a promising diagnostic tool for clinical assessment.

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“…Additionally, because of its rough carbon surface, carbon nanomaterials such as carbon nanotubes [43], graphene [44] and carbon nanocomposites [45] can be easily immobilized onto SPE by adsorption with a procedure of drop casting.…”

Section: Introductionmentioning

confidence: 99%

β-Cyclodextrin inclusion complex as the immobilization matrix for laccase in the fabrication of a biosensor for dopamine determination

Hua

Qin

Bai

et al. 2015

Sensors and Actuators B: Chemical

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Development of an Electrochemical Sensor Based on Reduced Graphene Oxide Modified Screen‐Printed Carbon Electrode for the Determination of Buprenorphine

Cited by 24 publications

References 42 publications

Tackling the Problem of Sensing Commonly Abused Drugs Through Nanomaterials and (Bio)Recognition Approaches

Tackling the Problem of Sensing Commonly Abused Drugs Through Nanomaterials and (Bio)Recognition Approaches

A Sensitive and Disposable Graphene Oxide Electrochemical Immunosensor for Label-free Detection of Human Immunoglobulin G

β-Cyclodextrin inclusion complex as the immobilization matrix for laccase in the fabrication of a biosensor for dopamine determination

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