2008
DOI: 10.1007/s12199-008-0050-0
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Development of a questionnaire to assess ‘Hie’ symptoms using an evidence-based analysis

Abstract: Objectives Certain symptoms and signs are culturally specific. 'Hie' (chill sensation) is a major symptom experienced by Japanese people; however, it is not easily understood by Westerners. Although Hie is not lifethreatening, it greatly hampers the quality of life in sufferers. To develop a remedy for Hie, valid and reliable measures are required. This is the first study aimed at developing a standardized questionnaire to quantitatively measure Hie symptom. Methods This was a cross-sectional study. To identif… Show more

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Cited by 7 publications
(3 citation statements)
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“…A feeling of coldness is one of the most frequent complaints in women [1][2][3], and approximately 50-60% of patients visiting general gynecological clinics in Japan have reported feeling cold [4][5][6]. Coldness is often referred to as 'hie-sho' (cold syndrome) in Japanese.…”
Section: Introductionmentioning
confidence: 99%
“…A feeling of coldness is one of the most frequent complaints in women [1][2][3], and approximately 50-60% of patients visiting general gynecological clinics in Japan have reported feeling cold [4][5][6]. Coldness is often referred to as 'hie-sho' (cold syndrome) in Japanese.…”
Section: Introductionmentioning
confidence: 99%
“…It has been suggested that the traditional herbal medicine had vasodilating action on peripheral DOI:10.5138/09750185.1880 Eastern women. Beside speripheral coldness in the hands and feet, other symptoms such as fatigue and depressive moods are often complicating [1].The pathophysiology of peripheral coldness is not well established, reduction of peripheral blood .The local mechanisms that the local cooling on cutaneous leads to the generation of reactive oxygen species (ROS), which stimulate intracellular signaling and the subsequent translocation of adrenoceptors to the plasma membrane for , thereby augmenting vasoconstriction peripheral coldness has not been established. It has been suggested that the administration of had vasodilating action on peripheral vessels and increased the blood flow under cold stress The fruits of Lycium barbarum, have a long tradition of use in nutrition and traditional medicine in East Asia.…”
Section: Introductionmentioning
confidence: 99%
“…Peripheral coldness is a common symptom in Japanese women, often complicating other symptoms such as headaches, depressive moods, and fatigue [1-3]. Whilst it is not a fatal disease, it can lead to a decreased quality of life [4].…”
Section: Introductionmentioning
confidence: 99%