“…Etodolac is chemically as 1, 8-Diethyl-1, 3, 4, 9-tetrahydropyrone (3, 4-b) indole -1-acetic acid. It is a racemic mixture of [+] S enantiomers and [-] R enantiomers 1 .Etodolac is belongs to pyranocarboxylic acid class of non-steroidal anti-inflammatory drug, developed in the 1970s 2 .It is used for rheumatoid arthritis and osteoarthritis, postoperative pain and inflammation 3 , and used as analgesic, anti-inflammatory agent, antipyretic and cyclooxygenase inhibitor. The mechanism of action of Etodolac is mainly prostaglandin synthetase enzyme inhibition.…”