Determination of Total Phenolic Content and NIR-Chemometrics Classification Model of Queen and Local Varieties of Soursop (&lt;i&gt;Annonamuricata&lt;/i&gt; L.) Leaf Powder

Wulandari, Lestyo; Dewi, Mellda Kusuma Candra; Kristiningrum, Nia; Siswanti, Yashinta Nirmala

doi:10.22146/ijc.43051

Cited by 5 publications

(3 citation statements)

References 20 publications

(25 reference statements)

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“…Soursop fruit has a high content of antioxidants such as tannins, alkaloids, flavonoids, phenolics, and ascorbic acid so that it can neutralize radical substances formed in body cells [16,17]. These results are consistent with previous studies which stated that soursop fruit contains flavonoids which function to suppress cholesterol synthesis in the liver by the HMG-CoA reductase enzyme by competitively binding to its cofactor site, similar to patent cholesterol drugs of the statin class such as simvastatin [18,19].…”

Section: Discussionsupporting

confidence: 87%

Hypocholesterolemic and Hypoglycemic Effects of Soursop Fruit (Annona muricata) Ethanolic Extract in High Fat Diet and Alloxan Induced Wistar Rats

Sovia¹,

Nazarudin²,

Fiddiyanti³

et al. 2022

Proceedings of the 13th Annual Scientific Conference of Medical Faculty, Universitas Jenderal Achmad Yani (ASCMF 2022)

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Annona muricata (soursop) is a plant belonging to the Annonaceae family. It's a medicinal herb that's been used for centuries as a natural cure for a number of diseases. Several investigations in animals showed that the bark and leaves of the plant possessed antihypertensive, vasodilator, anti-spasmodic, and cardio depressive. However, research on soursop fruit is still limited. This study aims to investigate the effect of soursop fruit ethanolic extract on blood glucose, total and Low-Density Lipoprotein (LDL) cholesterol levels in high fat diet and alloxan-induced rats (Rattus novergicus). The study was done experimentally with pre and posttest control group design using 30 rats divided into 6 groups consisted of normal group with standard diet, and five groups induced by high fat diet and alloxan then given 0.9 mg/kg of simvastatin, 0.5 mg/kg glibenclamide, 250 and 500 mg/kg of soursop fruit ethanolic extract (SFEE), and one diabetic hyperglycmia group as positive control without treatment. Blood glucose, total and LDL cholesterol levels measurement was conducted after 21 days of treatment. Data was analyzed using dependent t-test. Results shows significant reduction in blood glucose, total and LDL cholesterol level within treatment groups (p < 0.05). Furthermore, 500 mg/kg SFEE has roughly the same effectiveness as 0.9 mg/kg of simvastatin in reducing the total cholesterol level (p > 0.05), but not for LDL cholesterol. Meanwhile, the effectiveness of 250 and 500 mg/kg SFEE in lowering blood glucose levels is the same as glibenclamide (p > 0.05). In conclusion, SFEE shows hypoglycemic and hypocholesterolemic effect on both dosages.

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Section: Discussionsupporting

confidence: 87%

Hypocholesterolemic and Hypoglycemic Effects of Soursop Fruit (Annona muricata) Ethanolic Extract in High Fat Diet and Alloxan Induced Wistar Rats

Sovia¹,

Nazarudin²,

Fiddiyanti³

et al. 2022

Proceedings of the 13th Annual Scientific Conference of Medical Faculty, Universitas Jenderal Achmad Yani (ASCMF 2022)

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“…Aktivitas antioksidan ini dapat menghambat stres oksidatif. Aktivitas antioksidan tersebut terkait dengan kandungan senyawa kimia yang tinggi pada berbagai bagian tubuh tumbuhan ini (Wulandari et al, 2020).…”

Section: Pendahuluanunclassified

ANALISIS KADAR FLAVONOID TOTAL FRAKSI ETIL ASETAT KULIT BATANG SIRSAK (Annona muricata L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS

Mashar¹,

Annah²,

Dali³

et al. 2023

jofar

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Pendahuluan: Sirsak merupakan tanaman yang memiliki buah dengan kandungan nutrisi dan senyawa kimia yang telah banyak digunakan untuk pengobatan tradisional, dan kaya akan senyawa antioksidan. Aktivitas antioksidan ini dapat menghambat stres oksidatif. Aktivitas antioksidan tersebut terkait dengan kandungan senyawa kimia yang tinggi pada berbagai bagian tubuh tumbuhan ini. Klika sirsak mengandung berbagai senyawa, salah satunya adalah flavonoid. Flavonoid memiliki efek biokimia dan antioksidan yang banyak dimanfaatkan untuk meningkatkan kesehatan. Berbagai penelitian melaporkan bahwa flavonoid memiliki potensi sebagai anti inflamasi, anti alergi, antivirus, antikarsinogenik, serta terapeutik dan sitotoksik. Tujuan: Penelitian ini bertujuan untuk menganalisis kadar flavonoid total ekstrak etil asetat klika sirsak dengan metode spektrofotometri UV-VIS. Metode: Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol, dan dilanjutkan dengan proses partisi dengan pelarut etil asetat sehingga diperoleh ekstrak etil asetat. Analisis kadar flavonoid total dilakukan dengan metode spektrofotometri UV-Vis menggunakan larutan baku rutin pada konsentrasi 10, 20, 30, dan 40 ppm. Absorbansi larutan baku rutin dan ekstrak diukur pada Panjang gelombang 415 nm. Hasil: Hasil ekstraksi dengan pelarut etanol dan dilanjutkan dengan proses partisi dengan pelarut etil asetat diperoleh ekstrak etil asetat sebanyak 1,6 g dan nilai rendemen sebesar 10,67%. Hasil analisis kadar flavonoid total sampel dan didapatkan hasil yaitu kadar flavonoid total dari ekstrak etil asetat klika sirsak adalah 118,266 mg ER/g dengan persentase 11,8266 %. Kesimpulan: Ekstrak etil asetat klika sirsak positif mengandung flavonoid dan sebanyak 1 mg/mL sampel mengandung flavonoid total sebesar 118,266 mg ER/g dengan persentase 11,8266 %.

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“…However, in the literature there is no description of the NIR spectrum of the baru seed oil, only the spectrum of the cross sections of the wood of its tree . Similarly, there is no NIR spectrum of soursop seed oil in the literature, only the FT-IR spectrum of the oil (Elagbar et al, 2016) and the NIR spectrum of the leaves of its tree (Wulandari et al, 2020). Figure 1 shows the two main absorption bands in the spectra of SO, SSO, and BO.…”

Section: Nir Spectroscopy Analysismentioning

confidence: 99%

Detection and characterization of adulterants in baru and soursop oils

Trindade

Colares

Souza

2023

Food Sci. Technol (Campinas)

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The presence of vegetable oils in the pharmaceutical and cosmetic industries boosts their production and commercialization, maximizing the economic potential, however to increase profits, vegetable oils with high added value are the target of adulteration practices. This negatively affects the quality of the product and compromises the bioactive properties of these oils. The objective of this study was to build partial least squares regression models to identify baru oil and soursop oil samples adulterated with soybean oil. For data collection the oils samples were characterized using portable near-infrared spectrometer and Fourier-transform infrared spectrometer. These techniques were chosen because both provide information about the functional groups of chemical compounds, however portable equipment, being cheaper, presents signals with lower spectral resolution. Thus, the objective of the work is also to verify if the results using both equipment are similar. The developed regression models were effective; however, the near-infrared technique presented some limitations in the identification of soursop oil. This is because for the construction of his model it was necessary to use a smaller number of variables and levels of adulteration. Nevertheless, high R² values and relatively low errors were obtained for all models, making it possible to identify the adulteration. Pratica Application: Adulteration analysis of baru and soursop oils by infrared spectroscopy and portable equipment

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Determination of Total Phenolic Content and NIR-Chemometrics Classification Model of Queen and Local Varieties of Soursop (<i>Annonamuricata</i> L.) Leaf Powder

Cited by 5 publications

References 20 publications

Hypocholesterolemic and Hypoglycemic Effects of Soursop Fruit (Annona muricata) Ethanolic Extract in High Fat Diet and Alloxan Induced Wistar Rats

Hypocholesterolemic and Hypoglycemic Effects of Soursop Fruit (Annona muricata) Ethanolic Extract in High Fat Diet and Alloxan Induced Wistar Rats

ANALISIS KADAR FLAVONOID TOTAL FRAKSI ETIL ASETAT KULIT BATANG SIRSAK (Annona muricata L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS

Detection and characterization of adulterants in baru and soursop oils

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