Determination of phenolic compounds and antioxidant activity in passion fruit pulp (Passiflora spp.) using a modified QuEChERS method and UHPLC-MS/MS

Rotta, Eliza Mariane; Rodrigues, Carina Alexandra; Jardim, Isabel Cristina Sales Fontes; Maldaner, Liane; Visentainer, Jesuí Vergílio

doi:10.1016/j.lwt.2018.10.052

Cited by 54 publications

(22 citation statements)

References 24 publications

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“…A limited number of studies have investigated the composition of fruits from passifloras. In two prior studies, pelargonidin, quercetin, and luteolin derivatives were identified in P. edulis f. Flavicarpa, P. edulis, P. alata, and Passiflora ligularis [7,8]. However, in this study, cyanidin 3-rutinoside, ferulic acid, (+)-catechin, and (−)-epicatechin were identified in Colombian passion fruits.…”

Section: Discussioncontrasting

confidence: 69%

“…Example chromatograms for reference standards are presented in Figure A1 (Appendix A.). Despite multiple studies highlighting the uses of tropical fruit flavonoids for the control of free radicals (natural antioxidants) [7,8], or the regulation of fungal and bacterial activities [9], information on anti-inflammatory activity is lacking. Granadilla, Gulupa, and Maracuyá (passion fruits) are promising fruits for further study because of their proven medicinal benefits [8].…”

Section: Uhplc-ms Analysis Of Passiflora Extractsmentioning

confidence: 99%

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Polyphenol Extracts from Three Colombian Passifloras (Passion Fruits) Prevent Inflammation-Induced Barrier Dysfunction of Caco-2 Cells

et al. 2019

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Chronic intestinal inflammation is associated with pathophysiology of obesity and inflammatory bowel diseases. Gastrointestinal inflammation increases barrier dysfunction exacerbating the immune response and perpetuating chronic inflammation. Anti-inflammatory flavonoids may prevent this intestinal barrier dysfunction. The purpose of this study was to evaluate the polyphenol composition of Colombian Passiflora edulis var. Flavicarpa (Maracuyá), Passiflora edulis var. Sims (Gulupa), and Passiflora ligularis var. Juss (Granadilla) (passion fruits) and to evaluate their ability to inhibit disruption of intestinal barrier dysfunction of Caco-2 (colorectal adenocarcinoma) cells by an inflammatory cocktail (IC). Polyphenols (flavan-3-ols, phenolic acids, flavonols), xanthenes, and a terpene were identified in passion fruits. Cyanidin 3-rutinoside, (+)-catechin and ferulic acid were the most abundant phenolics in P. edulis var. Flavicarpa, P. edulis var. Sims, and P. ligularis var. Juss, respectively. Fruit extracts prevented loss of transepithelial electrical resistance in Caco-2 cells treated with the IC. Among the extracts, P. ligularis var. Juss was most effective at maintaining Caco-2 transepithelial electrical resistance (TEER) with ~73% relative to the IC-treated cells with about 43% of initial TEER values. This fruit had cyanidin-3-rutinoside, (+)-catechin, (−)-epicatechin, and ferulic acid in its phenolic profile. Results of this work support the hypothesis that consumption of passion fruit extracts could benefit intestinal health.

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Section: Discussioncontrasting

confidence: 69%

Section: Uhplc-ms Analysis Of Passiflora Extractsmentioning

confidence: 99%

Polyphenol Extracts from Three Colombian Passifloras (Passion Fruits) Prevent Inflammation-Induced Barrier Dysfunction of Caco-2 Cells

et al. 2019

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“…Antioxidant, antimicrobial and cytotoxic activities of the anthocyanin extracts obtained from passion fruit epicarp using the optimized and conventional extraction methods. The antioxidant properties of passion fruit extracts have been reported by other authors, which measured this activity by different in vitro assays, such as ABTS, DPPH and FRAP [17][18][19], and pointed out a correlation between total phenolics and antioxidant capacity.…”

Section: Antioxidant Activitymentioning

confidence: 65%

Recovery of Anthocyanins from Passion Fruit Epicarp for Food Colorants: Extraction Process Optimization and Evaluation of Bioactive Properties

et al. 2020

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The potential of passion fruit (Passiflora edulis Sims) epicarp to produce anthocyanin-based colorants with bioactive properties was evaluated. First, a five-level three-factor factorial design coupled with response surface methodology was implemented to optimize the extraction of anthocyanins from dark purple epicarps. The extraction yield and cyanidin-3-O-glucoside content were used as response criteria. The constructed models were fitted to the experimental data and used to calculate the optimal processing conditions (t = 38 min, T = 20 °C, S = 0% ethanol/water (v/v) acidified with citric acid to pH 3, and RS/L = 50 g/L) that lead to maximum responses (3.4 mg/g dried epicarp and 9 mg/g extract). Then, the antioxidant, antimicrobial, and cytotoxic activities of anthocyanin extracts obtained using the optimized method and a conventional extraction method were evaluated in vitro. The extract obtained by the optimized method revealed a higher bioactivity, in agreement with the higher cyanidin-3-O-glucoside content. This study highlighted the coloring and bioactive potential of a bio-based ingredient recycled from a bio-waste, which promotes a sustainable bioeconomy in the agri-food sector.

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“…The passion fruit pulp is a famous food source of flavonoids, which contains 158.0 mg/ml of total flavonoids, 16.2 mg/ml of isoorientin (Zeraik and Yariwake, 2010) and 0.42 mg/g of quercetin (Rotta et al, 2019). The aerial parts of P. edulis extracted by reflux with 40% ethanol contain 0.90% of apigenin.…”

Section: Flavonoidsmentioning

confidence: 99%

Passiflora edulis: An Insight Into Current Researches on Phytochemistry and Pharmacology

Luan

Yang

et al. 2020

Front. Pharmacol.

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Passiflora edulis, also known as passion fruit, is widely distributed in tropical and subtropical areas of the world and becomes popular because of balanced nutrition and health benefits. Currently, more than 110 phytochemical constituents have been found and identified from the different plant parts of P. edulis in which flavonoids and triterpenoids held the biggest share. Various extracts, fruit juice and isolated compounds showed a wide range of health effects and biological activities such as antioxidant, anti-hypertensive, anti-tumor, antidiabetic, hypolipidemic activities, and so forth. Daily consumption of passion fruit at common doses is non-toxic and safe. P. edulis has great potential development and the vast future application for this economically important crop worldwide, and it is in great demand as a fresh product or a formula for food, health care products or medicines. This mini-review aims to provide systematically reorganized information on physiochemical features, nutritional benefits, biological activities, toxicity, and potential applications of leaves, stems, fruits, and peels of P. edulis.

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Determination of phenolic compounds and antioxidant activity in passion fruit pulp (Passiflora spp.) using a modified QuEChERS method and UHPLC-MS/MS

Cited by 54 publications

References 24 publications

Polyphenol Extracts from Three Colombian Passifloras (Passion Fruits) Prevent Inflammation-Induced Barrier Dysfunction of Caco-2 Cells

Polyphenol Extracts from Three Colombian Passifloras (Passion Fruits) Prevent Inflammation-Induced Barrier Dysfunction of Caco-2 Cells

Recovery of Anthocyanins from Passion Fruit Epicarp for Food Colorants: Extraction Process Optimization and Evaluation of Bioactive Properties

Passiflora edulis: An Insight Into Current Researches on Phytochemistry and Pharmacology

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