Determination of iodine in biological materials by neutron activation analysis

“…These include methods based on catalytic reactions [6,7], gas chromatography of iodine in the form of iodoacetone and iodobutanone [8], X-ray fluorescence spectrometry [4,9], the use of iodide-ion-selective electrodes [10,11] and most lately inductively coupled plasma mass spectrometry, especially with the isotope dilution method [12,13]. Two very sensitive methods for determination of traces of iodine, with the advantage of freedom from reagent blanks, are thermal neutron activation in either its destructive or radiochemical form [14,15], and epithermal neutron activation analysis for non-destructive determination of this element when its concentration is somewhat higher [16,17]. A rapid radiochemical activation analysis of different food articles and diets was previously developed and optimised for the determination of low concentration of iodine [18,19].…”

Section: Introductionmentioning

confidence: 99%

Iodine concentration in different human brain parts

Andrási¹,

Bélavári²,

Stibilj³

et al. 2004

Analytical and Bioanalytical Chemistry

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Iodine is one of the most important essential elements as demonstrated by the fact that its deficiency can cause goitre. Nevertheless, quantitative data on its concentration in biological materials, especially in the human brain, are scarce. There is therefore a demand for accurate and reliable information on iodine in these types of samples. The purpose of the present work was to determine the concentration of total iodine in some control human brain parts by rapid radiochemical neutron activation analysis. Our second goal was to determine I distribution between lipid fraction and in brain tissue without lipid by applying two types of solvent extraction methods. The results were checked by the analysis of biological standard reference materials with certified or literature values for iodine and good agreement was found.

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“…Radiochemical separation methods are based on precipitation of selenium (20), separation on aminoexchangers (66) and, most frequently, distillation 186 (35,89,98,112) and extraction (35,98,113). Byrne and Kosta (67,114,115) described a convenient method of simultaneous determination of mercury and selenium in biological samples pyrolyzed in a stream of oxygen and found (67) a correlation between the levels of mercury and selenium in humans exposed to inorganic mercury.…”

Section: Neutron Activation Analysis (Naa)mentioning

confidence: 99%