Determination of Anomalin and Deltoin in Seseli resinosum by LC Combined with Chemometric Methods

Tosun, Alev; Bahadır, Özlem; Dinç, Erdal

doi:10.1365/s10337-007-0392-6

Cited by 10 publications

(3 citation statements)

References 5 publications

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“…Isolation and purification procedures of anomalin are also summarized in Table 1. As can be seen, anomalin was obtained from either aerial part and roots of the plant by extraction with petroleum ether, [36,56,57,60,68] hexane, [59,62,[64][65][66][67] diethyl ether, [70] chloroform, [51] methanol, [24,26,38,39,45 -50,52 -54,61,69,70] ethanol, [40,44,55,73,74] acetone, [41,[57][58][59] etc. at room temperature or by reflux.…”

Section: Sources and Isolationmentioning

confidence: 99%

A Review on Anomalin: A Natural Bioactive Pyranocoumarin from the Past to the Future

Önder

Трендафилова

2022

Chemistry & Biodiversity

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Anomalin is a seselin-type pyranocoumarin isolated for the first time from Angelica anomala Avé-Lal, but is also found in several other plant species, especially in Apiaceae. This lipophilic molecule possesses pharmacologically beneficial activities for human health. The major scientific databases Scopus, Web of Science, Google Scholar, and PubMed up to the end of 2021 and the combining terms anomalin, praeruptorin, isolation, structure elucidation, and biological activity were used in the research of this review. This review focuses on the sources, structural properties, and biological functions of anomalin and provides future trends in the investigation of anomalin, particularly in therapies for many common diseases such as anti-inflammatory and neurodegenerative illnesses. As a potential bioactive molecule, prospective studies on anomalin should be done through supported clinical trials. At the end, this review confirms the significant pharmacological potential of anomalin.

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Section: Sources and Isolationmentioning

confidence: 99%

A Review on Anomalin: A Natural Bioactive Pyranocoumarin from the Past to the Future

Önder

Трендафилова

2022

Chemistry & Biodiversity

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“…In mass spectra, angular plots between loadings characteristic of individual compounds and the remaining diagnostic masses revealed further mass spectral structure [Zissis et al,1999]. Liquid chromatography-chemometric methods [LC-Partial least squares (LC-PLS), LCprinciple component regression (LC-PCR) and LC-artificial neural network (LC-ANN)] were developed for the determination of anomalin (ANO) and deltoin (DEL) in the root by Alev Tosun et al [ Tosun et al,2007]. Firstly, chemometric conditions were optimized by testing different mobile phases at various proportions of solvents with various flow rates in different wavelengths by using a normal phase column to obtain the best separation and recovery results.…”

Section: Chemometrics Investigations Using Photo Diode Array Detectionmentioning

confidence: 99%

Photodiode Array Detection in Clinical Applications; Quantitative Analyte Assay Advantages, Limitations and Disadvantages

Es’haghi¹

2011

Photodiodes - Communications, Bio-Sensings, Measurements and High-Energy Physics

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“…Nowadays, chemometric methods, particularly partial least squares (PLS) and principal component regression (PCR), have been used as chemometric powerful tools to quantify two or more active substances in their mixtures using spectrophotometric data. However, some application of the chemometric calibration techniques in the chromatographic analysis of complex samples were reported 10–12.…”

Section: Introductionmentioning

confidence: 99%

New HPLC‐chemometric approaches to the analysis of isoflavones in Trifolium lucanicum Gasp.

Küçükboyacı

Güvenç

Dinç

et al. 2010

J of Separation Science

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New HPLC-chemometric approaches were proposed for the simultaneous chromatographic quantification of daidzein, genistein, formononetin, and biochanin A in the samples consisting of the aerial parts of Trifolium lucanicum Gasp. (Leguminosae). Partial least squares and principal component regression algorithms were applied to the multiple chromatographic data set obtained by measuring at 240, 248, 256, and 264 nm to construct HPLC-partial least squares and HPLC-principal component regression calibrations. Chromatographic separation was carried out by using a mobile phase containing methanol, acetate buffer (pH=4.75) and acetonitrile (21:58:21, v/v/v) on the reversed phase column, Supelcosil™ LC-18 (15 cm×4.6 mm id). In addition, conventional HPLC based on the detection at a single wavelength was used for the determination of each compound in the extracts of T. lucanicum. The validity and applicability of the proposed HPLC-chemometric and conventional HPLC methods were performed by analyzing various synthetic plant samples. A good agreement was observed in the application of the proposed HPLC-chemometric tools to the synthetic and extracted samples of T. lucanicum.

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Determination of Anomalin and Deltoin in Seseli resinosum by LC Combined with Chemometric Methods

Cited by 10 publications

References 5 publications

A Review on Anomalin: A Natural Bioactive Pyranocoumarin from the Past to the Future

A Review on Anomalin: A Natural Bioactive Pyranocoumarin from the Past to the Future

Photodiode Array Detection in Clinical Applications; Quantitative Analyte Assay Advantages, Limitations and Disadvantages

New HPLC‐chemometric approaches to the analysis of isoflavones in Trifolium lucanicum Gasp.

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