Determination and correlation of solubility and thermodynamic properties of l -methionine in binary solvents of water + (methanol, ethanol, acetone)

Zhang, Teng; Li, Zhenfang; Wang, Yan; Liu, Cong; Chen, Yuanfu; Zheng, Xiaochen; Jiang, Lei; Gong, Junbo

doi:10.1016/j.jct.2015.12.022

Cited by 38 publications

(27 citation statements)

References 30 publications

(44 reference statements)

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“…The standard uncertainties in the temperature and enthalpy of fusion are 0.5 K and 0.02 kJ mol −1 , respectively. Otherwise, it can be calculated by eq 24: 41 = Δ Δ T H S m fus fus (24) Where T m represent the melting point, Δ fus H, Δ fus S are enthalpy of fusion, entropy of melting, respectively. 3.4.2.…”

Section: Cnibs/r-k Equationmentioning

confidence: 99%

Solubility of Benzoin in Six Monosolvents and in Some Binary Solvent Mixtures at Various Temperatures

Yang

Tang

et al. 2017

J. Chem. Eng. Data

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The solubility of benzoin in monosolvents (acetone, ethyl acetate, methanol, ethanol, 1-propanol, and 1-butanol) and binary solvent mixtures (ethyl acetate + methanol, ethyl acetate + ethanol) was measured using UV–vis spectroscopy at temperatures ranging from 283.15 K to 323.15 K. It can be seen from the data that the solubility of benzoin increases expectedly as temperature increases in a given solvent or solvent mixture, the solubility in acetone is maximum among six monosolvents which could be well explained by the existence of strong H-bonds, rather than the “like dissolves like” rule. In binary solvent mixtures, the solubility reaches maximum when the mole fraction of methanol is 0.1 in ethyl acetate + methanol mixed solvents, while the maximum exhibits at 0.2 of mole fraction of ethanol in ethyl acetate + ethanol. The solubility parameter was interpreted as the cosolvency of benzoin solubility in binary solvent mixtures. The solubility data were correlated by modified Apelbalt equation, CNIBS/R-K equation, λh equation, Jouyban–Acree model, and Van’t–JA equation. Mixing thermodynamic properties were further calculated and discussed regarding their roles in dissolution and solubility.

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Section: Cnibs/r-k Equationmentioning

confidence: 99%

Solubility of Benzoin in Six Monosolvents and in Some Binary Solvent Mixtures at Various Temperatures

Yang

Tang

et al. 2017

J. Chem. Eng. Data

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“…In addition, it can be found from Table S5 and Figure S1 of the Supporting Information that the dielectric constants of solvents, methanol, ethanol, and acetone, decrease with increasing temperature, which can describe the solubility’s evolution to a certain extent. The solubility of FOM-Na may also be affected by some other factors, such as hydrogen bonds, ionization constant, and surface tension of the different solvents and so on. − …”

Section: Results and Discussionmentioning

confidence: 99%

Solubility Measurement and Correlation of Fosfomycin Sodium in Six Organic Solvents and Different Binary Solvents at Temperatures between 283.15 and 323.15 K

et al. 2017

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The solubility data of fosfomycin sodium (FOM-Na) in six pure solvents (methanol, ethanol, propanol, cyclohexane, acetone, N,N-dimethylformamide) and two binary solvents (methanol + ethanol, methanol + acetone) at temperatures ranging from 283.15 to 323.15 K were measured by a laser monitoring dynamic method at atmospheric pressure. It turned out that the solubility data decreased with increasing temperature, and also varies with the composition of the solvents. Moreover, the experimental data in pure solvents have been correlated with two thermodynamic models (i.e., modified Apelblat and van’t Hoff), and the data in binary solvents have been correlated with CNIBS/R-K equation and two modified versions of Jouyban–Acree models (Van’t-JA equation and Apel-JA equation), respectively. All the results showed a good agreement with the experimental data. Intermolecular interaction force and dielectric constants are introduced to explain the relationship between solubility and temperature. In addition, the analysis of the solubilities implies that higher temperature may destroy the forces between the solvent and solute molecules, leading to lower solubility. And this can give a guide to the design and optimization of the crystallization process of FOM-Na in the industry.

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“…During experiment, the solubility data of bisacodyl in DMF, 1,4-dioxane, NMP, methanol, ethanol, n -propanol, isopropanol, 1-butanol, ethyl acetate, acetone, acetonitrile, and toluene were obtained by using the isothermal saturation method. − Excess bisacodyl was added into a 50 mL jacketed glass vessel containing 30 mL of corresponding solvent. The temperature of the vessel was kept through circulating water, and the real temperature was displayed by using a mercury glass microthermometer, the standard uncertainty of which is 0.05 K. A reflux condenser was directly connected to the vessel to prevent solvent evaporation.…”

Section: Methodsmentioning

confidence: 99%

Solubility of Bisacodyl in Pure Solvent at Various Temperatures: Data Correlation and Thermodynamic Property Analysis

Yan

et al. 2019

J. Chem. Eng. Data

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In this work, the solubility data of bisacodyl in N,N-dimethylformamide (DMF), 1,4-dioxane, N-methyl pyrrolidone (NMP), methanol, ethanol, n-propanol, isopropanol, 1-butanol, ethyl acetate, acetone, acetonitrile, and toluene at temperatures ranging from 273.15 to 313.15 K at atmospheric pressure were obtained by the isothermal saturation method. The maximum value was found in pure DMF, followed by the sequence of NMP > 1,4-dioxane > acetone > acetonitrile > ethyl acetate > toluene > 1-butanol > n-propanol > methanol > ethanol > isopropanol. The results were correlated with the modified Apelblat equation and λh equation. The maximum value of relative average deviations (RADs) was obtained in isopropanol solution (2.82 × 10 –2) by the λh equation, and the largest root-mean-square deviation (RMSD) is obtained by the λh equation (0.66 × 10–4) in acetone, which indicates that the experimental data are consistent with the calculated. The obtained solubility data would be very useful for optimizing the purification process of bisacodyl.

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Determination and correlation of solubility and thermodynamic properties of l -methionine in binary solvents of water + (methanol, ethanol, acetone)

Cited by 38 publications

References 30 publications

Solubility of Benzoin in Six Monosolvents and in Some Binary Solvent Mixtures at Various Temperatures

Solubility of Benzoin in Six Monosolvents and in Some Binary Solvent Mixtures at Various Temperatures

Solubility Measurement and Correlation of Fosfomycin Sodium in Six Organic Solvents and Different Binary Solvents at Temperatures between 283.15 and 323.15 K

Solubility of Bisacodyl in Pure Solvent at Various Temperatures: Data Correlation and Thermodynamic Property Analysis

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