Determinants of radial artery pulse wave analysis in asymptomatic individuals

Abstract

Diastolic and systolic indices of pulse contour analysis correlate differently with traditional risk factors in men and women.

Family History of Hypertension and Arterial Elasticity Characteristics in Healthy Young People

“…Grey et al (29) reported that reduced small artery elasticity, as a measure of endothelial dysfunction, is significantly associated with CV events independent of age. Another study showed that small arterial compliance may correlate closely with BP (30). Our study has shown that C2 was significantly lower in offspring of hypertensive parents, independent of SBP, DBP, and heart rate; thus, C2 may prove to be an early and sensitive marker for the presence of disease.…”

Synergistic effect of smoking and blood pressure on augmentation index in men, but not in women

“…Several studies have shown that hypertension, abnormal glucose metabolism, adiposity, smoking and heart rate are related to AI. [7][8][9][10][11]21 In the present study, although blood pressure was an independent variable related to increased AI in men and women at any age, the significance of smoking related to increased AI was limited to men of any age and women aged o50 years. To the best of our knowledge, this study is the first to suggest the gender-related difference of the relationship between risk factors for CVD and AI even in healthy individuals.…”

“…[4][5][6] Some studies reported that CVD risk factors affect AI. [7][8][9][10][11] The age-related increase in AI shows an attenuated curve in subjects aged 450 years, and AI is thought to be less sensitive in reflecting arterial stiffness in elderly subjects. 12 Although AI increases predominantly in women, the Second Australian National Blood Pressure Study (ANBP 2 study) showed that it cannot be used as a marker for predicting future CVD events in elderly women with hypertension.…”

Rapid onset and offset of circulatory adaptations to exercise training in men

“…31,32 It was therefore possible that elevated arterial compliance contributed to the increased vascular conductance and lowered BP that we saw. We used two separate indices of pulse wave reflection [17][18][19] to evaluate this, but neither index was altered with training. Thus, we find no support for endothelium-mediated elevation of arterial compliance contributing to the adaptive response to exercise, at least under our study conditions.…”

“…The phasic BP waveform was used to derive two indices of peripheral wave reflection that are proportional to arterial stiffness ( Figure 1). The first of these was the reflection time (ms) between the primary and secondary (reflected) peaks on the pressure wave, 17,18 the second was the radial augmentation index, which represents the ratio between the amplitudes of primary and secondary peaks. 19 Time course of circulatory adaptations to training Á Murray et al…”