DETECTION OF RUBELLA-SPECIFIC IgM IN SUBCLINICAL RUBELLA REINFECTION IN PREGNANCY

Morgan‐Capner, P.; Hambling, M.H.; Coleman, T. J.; Watkins, R; Stern, H.; Hodgson, Julian; Dulake, C.; Boswell, P.A; Booth, J. C.; Best, Jennifer M.; Banatvala, J. E.

doi:10.1016/s0140-6736(85)91027-x

Cited by 76 publications

(2 citation statements)

References 18 publications

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“…Although antibody titers after vaccination may decline to low or undetectable levels over time, more sensitive assays, such as the enzyme immunoassay and virus neutralization tests, typically detect rubella antibody in such persons (28)(29)(30)(31). Although fetal infection has been recognized after maternal reinfection (33-36) following both naturally acquired and vaccine-induced immunity, the risk of fetal damage remains low (34,37). Although fetal infection has been recognized after maternal reinfection (33-36) following both naturally acquired and vaccine-induced immunity, the risk of fetal damage remains low (34,37).…”

Section: Recent Resurgence Of Rubellamentioning

confidence: 99%

Update: Rubella and Congenital Rubella Syndrome, 1980–1990

Lindegren

Fehrs

Hadler

et al. 1991

Epidemiologic Reviews

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Section: Recent Resurgence Of Rubellamentioning

confidence: 99%

Update: Rubella and Congenital Rubella Syndrome, 1980–1990

Lindegren

Fehrs

Hadler

et al. 1991

Epidemiologic Reviews

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“…Kızamık.çık akut dönem humoral cevabında IgM tipi antikorlar ortaya çıkmaktadır. Rubella IgM akut, aktif infeksiyonu veya reinfeksiyonu düşündürmektedir (6,7,8).…”

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Diagnosis of Rubella in the Childhood With Detection of IgM Antibodies

Cengiz¹,

Kıyan²,

Dolapçi³

et al. 1995

Eur J Ther

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Permanent immunization against rubella virus develops both after natural infection with rubella virus and after active immunization, but reinfections can be occured. For that reason, it is necessary to determine the serologic profile of people. In the study, 175 sera of the children taken from Ankara University Medical School, Department of Pediatrics were tested by Elisa to detect rubella IgM antibodies in Ankara University Medical School, Department of Microbiology and Clinical Microbiology Elisa Laboratory. Only 1 seropositive case was found among 175 cases(0.57 %). This finding indicates the high percentage of natural immunization and some of active immunization among children.

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Some Current Issues Relating to Rubella Vaccine

Preblud¹

1985

JAMA

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At the time of licensure in 1969, available data indicated that rubella vaccines were safe, noncommunicable, and effective. Since vaccine virus could cross the placenta and infect the fetus, cautious use of the vaccines in childbearing-age women was recommended. Over the past 15 years, additional information about the vaccines has been accumulated. This article provides an update of data on (1) the risk and degree of joint symptoms following vaccination and revaccination, (2) the duration of vaccine-induced immunity, (3) the protective effect of low levels of vaccine-induced antibody, and (4) the risks to the fetus following maternal vaccination. The data support continued vaccination of all young children as well as increased efforts to vaccinate susceptible adolescents and young adults, especially women. Only by more effective vaccination of the latter can elimination of congenital rubella syndrome be hastened.

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DETECTION OF RUBELLA-SPECIFIC IgM IN SUBCLINICAL RUBELLA REINFECTION IN PREGNANCY

Cited by 76 publications

References 18 publications

Update: Rubella and Congenital Rubella Syndrome, 1980–1990

Update: Rubella and Congenital Rubella Syndrome, 1980–1990

Diagnosis of Rubella in the Childhood With Detection of IgM Antibodies

Some Current Issues Relating to Rubella Vaccine

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