Detection of Microecological Phenomena in Filled Teeth I. Phenomena in Gap Between Restoration and Cavity Wall

Buchmann, G.; Klimm, W; Gabert, A; Edelmann, Johannes

doi:10.3109/08910609009140118

Cited by 6 publications

(2 citation statements)

References 13 publications

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“…The colonization of dentine bur grooves by bacteria provides an insight into where protected niches may arise in the restoration/cavity interface. The presence of filaments bridging cracks and voids within the restoration and cavity wall, and cocci colonizing the smoother dentine surface has been reported in a study on extracted teeth by Buchmann et al . (1990).…”

Section: Discussionsupporting

confidence: 57%

A new in vitro model for the study of microbial microleakage around dental restorations: a preliminary qualitative evaluation

Matharu¹,

Spratt²,

Pratten³

et al. 2001

Int Endodontic J

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Section: Discussionsupporting

confidence: 57%

A new in vitro model for the study of microbial microleakage around dental restorations: a preliminary qualitative evaluation

Matharu¹,

Spratt²,

Pratten³

et al. 2001

Int Endodontic J

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“…[20] Streptococcus mutans, one of the primary inhabitants present in saliva and at the restoration material-tooth interface, is regarded as the chief etiological agent responsible for dental caries. [21,22] During the demineralization of the enamel organ, it is possible to observe white opaque lesions of the enamel to the junction between the brackets and the enamel. ese lesions are minimal in general and not extended.…”

Section: Introductionmentioning

confidence: 99%

Biodegradation of orthodontic composites by Streptococcus mutans: An in vitro qualitative and quantitative assessment

Bationo

Beugré-Kouassi

Jordana

et al. 2020

APOS

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Objectives: The purpose of this study was to evaluate the degradation products of orthodontic composites (Grengloo, Blugloo, Transbond XT, and Transbond LR) by Streptococcus mutans and then to quantify the levels of released bisphenol A (BPA) using gas-phase chromatography and mass spectrometry (GC–MS). Materials and Methods: Orthodontic light-cured composite discs were incubated at 37°C in brain heart infusion (BHI) (control group) and in a culture of S. mutans with BHI (test group). Incubation solutions were collected every 48 h in each group and replaced with fresh solutions. These incubation solutions were accumulated and grouped. The assessment of degradation products from composites was done at 1 and 30 days. Detected BPA was then quantified. The limit of quantification was 0.01 μg/mL. Results: Degradation products were present at day 30. For the test group, BPA was detected in Blugloo at day 1 (0.38 μg/mL) and triethylene glycol dimethacrylate (TEGDMA) was detected in Grengloo and Transbond LR at day 1. Conclusion: S. mutans can hydrolyze long-term orthodontic composites. Monomers such as BPA and TEGDMA may be present in degradation products. It is possible to separate and identify leaching compounds by GC–MS technique.

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Composite resin degradation products from BisGMA monomer modulate the expression of genes associated with biofilm formation and other virulence factors in Streptococcus mutans

Singh

Khalichi

Cvitkovitch

et al. 2008

J Biomedical Materials Res

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Bacterial microleakage along the tooth/composite resin dental restoration interface contributes to postoperative sensitivity, recurrent caries, and necrosis. Studies have confirmed that enzymes in human saliva degrade composite resin monomers 2,2-bis [4-(2-hydroxy-3-methacryloxypropoxy) phenyl] propane (BisGMA) and triethylene glycol dimethacrylate (TEGDMA) to release methacrylic acid (MA), bishydroxypropoxyphenyl propane (Bis-HPPP), and triethylene glycol (TEG) at levels of 50 microM in vivo. Studies have found that TEGDMA degradation products alter the growth and gene expression of cariogenic Streptococcus mutans. Specifically, TEG was shown to alter S. mutans gene expression levels of gtfB, a known virulence factor, and yfiV, a putative transcriptional regulator of cell-surface fatty acid genes. The objective of this study was to examine the effect of BisGMA degradation products on the growth and gene expression of S. mutans NG8 cells. Results demonstrated slight inhibition of bacterial growth at Bis-HPPP concentrations of 1.0 x 10(2) and 2.5 x 10(2) microM at pH 5.5. Furthermore, both MA and Bis-HPPP affected gtfB and yfiV expression in a concentration-dependent manner. Because BisGMA is universally used across most dental restorative materials, with millions of placement procedures performed annually, these findings are relevant due to the potential influence of resin monomer-derived biodegradation products on biofilm formation, acid tolerance, and proliferation of S. mutans cells.

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Detection of Microecological Phenomena in Filled Teeth I. Phenomena in Gap Between Restoration and Cavity Wall

Cited by 6 publications

References 13 publications

A new in vitro model for the study of microbial microleakage around dental restorations: a preliminary qualitative evaluation

A new in vitro model for the study of microbial microleakage around dental restorations: a preliminary qualitative evaluation

Biodegradation of orthodontic composites by Streptococcus mutans: An in vitro qualitative and quantitative assessment

Composite resin degradation products from BisGMA monomer modulate the expression of genes associated with biofilm formation and other virulence factors in Streptococcus mutans

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