Detection of Leishmania (V) guyanensis in Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) collected from Pecari tajacu

Rojas‐Jaimes, Jesús; Correa-Núñez, Germán; Rojas, Nyshon; Cáceres-Rey, Omar

doi:10.7705/biomedica.v37i0.3435

Cited by 7 publications

(5 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, the role played by traditional hosts such as the two-toed sloth seems minimal in this outbreak. L. guyanensis has also been found in a Rhipicephalus microplus tick isolated from a peccary [44]. Interestingly, peccaries were the most frequent animal seen by soldiers in our study.…”

Section: Plos Neglected Tropical Diseasessupporting

confidence: 69%

Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects

et al. 2021

View full text Add to dashboard Cite

Background Cutaneous Leishmaniasis (CL) is endemic in French Guiana but cases are usually sporadic. An outbreak signal was issued on May 15th 2020 with 15 suspected cases after a military training course in the rainforest. An outbreak investigation was carried out. Methodology/Principal findings Thirty cases were confirmed. Leishmania guyanensis was the most frequent species (90%). The most frequent presentation was ulcerative (90%). Lesions on the face and hands were frequent (40% each). Eight cases (26%) presented a poor outcome after treatment with pentamidine and required a second line with amphotericin B. Three of them required further treatments with meglumine antimoniate or miltefosine. Two spots within the training area were deemed as likely sites of contamination, due to illegal logging. The isolated Leishmania strains did not form a separate cluster. Participation in Week 13 of year 2020 was associated with infection (OR = 4.59 [1.10–19.83]; p = 0.016) while undergoing only the “Fighting” exercise was protective (OR = 0.1 [0–0.74]; p = 0.021). There was no association between infection and other risk factors at the individual level. The attack rate of Regiment B (14/105 = 13.3%) was significantly higher (OR = 4.22 [1.84–9.53], p = 0.0001) compared to Regiment A (16/507 = 3.2%). The attack rate during this training course (30/858 = 3.5%) was significantly higher (OR 2.29 [1.28–4.13]; p = 0.002) than for other missions in French Guiana during the same period (22/1427 = 1.5%). Conclusions This outbreak could be explained by a combination of factors: climatic conditions around week 13, at-risk activities including night trainings, absence of impregnation, a lesser experience of rainforest duties in Regiment B and illegal logging attracting sandflies on military training grounds.

show abstract

Section: Plos Neglected Tropical Diseasessupporting

confidence: 69%

Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Although Leishmania spp. have been reported in ticks (L. infantum in R. sanguineus s.l., and L. guyanensis in R. microplus ticks in Peru, for example), the role of ticks in Leishmania transmission is still being debated, and no evidence of vector capacity has been reported yet [59][60][61]. Moreover, the finding of Leishmania spp.…”

Section: Discussionmentioning

confidence: 99%

Upscaling the Surveillance of Tick-Borne Pathogens in the French Caribbean Islands

et al. 2020

View full text Add to dashboard Cite

Despite the high burden of vector-borne disease in (sub)tropical areas, few information are available regarding the diversity of tick and tick-borne pathogens circulating in the Caribbean. Management and control of vector-borne disease require actual epidemiological data to better assess and anticipate the risk of (re)emergence of tick-borne diseases in the region. To simplify and reduce the costs of such large-scale surveys, we implemented a high-throughput microfluidic real-time PCR system suitable for the screening of the main bacterial and parasitic genera involved in tick-borne disease and potentially circulating in the area. We used the new screening tool to perform an exploratory epidemiological study on 132 adult specimens of Amblyomma variegatum and 446 of Rhipicephalus microplus collected in Guadeloupe and Martinique. Not only the system was able to detect the main pathogens of the area-Ehrlichia ruminantium, Rickettsia africae, Anaplasma marginale, Babesia bigemina and Babesia bovis-but the system also provided evidence of unsuspected microorganisms in Caribbean ticks, belonging to the Anaplasma, Ehrlichia, Borrelia and Leishmania genera. Our study demonstrated how high-throughput microfluidic real-time PCR technology can assist large-scale epidemiological studies, providing a rapid overview of tick-borne pathogen and microorganism diversity, and opening up new research perspectives for the epidemiology of tick-borne pathogens.

show abstract

“…En la investigación sobre la leishmaniasis se ha avanzado en su diagnóstico molecular dado que el diagnóstico clásico presente serias limitaciones. Colegas peruanos han desarrollado estudios moleculares para una detección rápida con una alta sensibilidad de las especies causales de la leishmaniasis en nuestro país contribuyendo de esta manera a la implementación terapéutica rápida y acertada por parte del personal médico; así como en el estudio de vectores y reservorios del parasito causal de la enfermedad (Tsukayama et al, 2013;Rojas-Jaimes et al, 2017). La tuberculosis la cual es un flagelo pandémico, en el Perú se ha avanzado en diferenciar síntomas e imágenes asociadas a tuberculosis, de neoplasias malignas descartando así linfomas, cáncer pulmonar y cerebral (Villena-Suarez et al, 2018).…”

Section: P L a S M O D I U M F A L C I P A R U Munclassified

Algunos Aportes Profesionales Del Biólogo en El Perú en El Campo De La Salud Pública: Conociendo Las Brechas Y Oportunidades

Rojas-Jaimes¹,

Correa-Núñez²

2020

View full text Add to dashboard Cite

El biólogo es el profesional de la ciencia que estudia la vida por excelencia, por tal su ámbito es sumamente amplio y diverso. El objetivo del presente estudio fue conocer los aportes del biólogo en el Perú en la Salud Publica y reconocer las brechas y oportunidades. Existen diversas áreas de la biología que repercuten fuertemente en la salud como la ecología que trata de entender en entorno que rodea al ser vivo y como este es influenciado por su medio, así también el microbiólogo que estudia los seres diminutos que contribuyen a la salud y a enfermedad. A pesar de que el aporte del biólogo es ampliamente reconocido en la mejora de nuestra sociedad y la existencia de notables biólogos peruanos que han aportado a nivel mundial en la salud pública como en la mejora del abastecimiento del agua, el diagnóstico rápido de los agentes causales de la tuberculosis y la leishmaniasis, diseño de vacunas promisorias contra la malaria y el descubrimientos de nuevos agentes infecciosos, existe muchas brechas en especial en el Perú para que esta profesión sea reconocida como se merece. Entre las limitantes en nuestro país están la ignorancia en muchos casos por la comunidad y sus dirigentes de lo que es un biólogo y como este aporta en mejorar la salud de la comunidad, resultando en un limitado incentivo y apoyo a la investigación. Por lo que se hace necesario una estrecha relación entre la información científica y el impacto social, difusión amplia, de acceso libre y entendible a toda la comunidad.

show abstract

Detection of Leishmania (V) guyanensis in Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) collected from Pecari tajacu

Cited by 7 publications

References 20 publications

Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects

Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects

Upscaling the Surveillance of Tick-Borne Pathogens in the French Caribbean Islands

Algunos Aportes Profesionales Del Biólogo en El Perú en El Campo De La Salud Pública: Conociendo Las Brechas Y Oportunidades

Contact Info

Product

Resources

About