Detection of influenza virus by a biosensor based on the method combining electrochemiluminescence on binary SAMs modified Au electrode with an immunoliposome encapsulating Ru (II) complex

Katayama, Yumi; Ohgi, Takayuki; Mitoma, Yoshiharu; Hifumi, Emi; Egashira, Naoyoshi

doi:10.1007/s00216-016-9587-8

Cited by 24 publications

(21 citation statements)

References 29 publications

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“…When antireflective chip condition was perturbed due to binding to, e.g., an antibody, the reflected light changes were quantitatively detected. Katayama et al [140] created an influenza virus biosensor based on two methods: electrochemiluminescence (ECL) of modified Au electrode combined with immunoliposome encapsulating Ru (II) complex. The authors have achieved sensitivity higher than ELISA; the detection range was from 2.7 × 10 2 to 2.7 × 10 3 PFU/mL.…”

Section: Novel Detection Methods Of Influenza Virusmentioning

confidence: 99%

Detection Methods of Human and Animal Influenza Virus—Current Trends

Dziąbowska¹,

Czaczyk²,

Nidzworski³

2018

Biosensors

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The basic affairs connected to the influenza virus were reviewed in the article, highlighting the newest trends in its diagnostic methods. Awareness of the threat of influenza arises from its ability to spread and cause a pandemic. The undiagnosed and untreated viral infection can have a fatal effect on humans. Thus, the early detection seems pivotal for an accurate treatment, when vaccines and other contemporary prevention methods are not faultless. Public health is being attacked with influenza containing new genes from a genetic assortment between animals and humankind. Unfortunately, the population does not have immunity for mutant genes and is attacked in every viral outbreak season. For these reasons, fast and accurate devices are in high demand. As currently used methods like Rapid Influenza Diagnostic Tests lack specificity, time and cost-savings, new methods are being developed. In the article, various novel detection methods, such as electrical and optical were compared. Different viral elements used as detection targets and analysis parameters, such as sensitivity and specificity, were presented and discussed.

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Section: Novel Detection Methods Of Influenza Virusmentioning

confidence: 99%

Detection Methods of Human and Animal Influenza Virus—Current Trends

Dziąbowska¹,

Czaczyk²,

Nidzworski³

2018

Biosensors

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“…Variations of this loaded immunoliposome platform have since been applied to the detection of the influenza virus biomarker hemagglutinin. 151,152…”

Section: Metal-based Signal Generationmentioning

confidence: 99%

Inorganic Complexes and Metal-Based Nanomaterials for Infectious Disease Diagnostics

et al. 2018

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Infectious diseases claim millions of lives each year. Robust and accurate diagnostics are essential tools for identifying those who are at risk and in need of treatment in low-resource settings. Inorganic complexes and metal-based nanomaterials continue to drive the development of diagnostic platforms and strategies that enable infectious disease detection in low-resource settings. In this review, we highlight works from the past 20 years in which inorganic chemistry and nanotechnology were implemented in each of the core components that make up a diagnostic test. First, we present how inorganic biomarkers and their properties are leveraged for infectious disease detection. In the following section, we detail metal-based technologies that have been employed for sample preparation and biomarker isolation from sample matrices. We then describe how inorganic- and nanomaterial-based probes have been utilized in point-of-care diagnostics for signal generation. The following section discusses instrumentation for signal readout in resource-limited settings. Next, we highlight the detection of nucleic acids at the point of care as an emerging application of inorganic chemistry. Lastly, we consider the challenges that remain for translation of the aforementioned diagnostic platforms to low-resource settings.

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“…Viruses are intracellular parasites unlike other microorganisms. These agents have only a few number of responsible genes for the synthesis of new viruses and most of them used different enzymes which created by the host cell [1]. So, fast and well-timed diagnosis of these diseases is very important due to the limited treatment options.…”

Section: Introductionmentioning

confidence: 99%

Nanomaterial-based biosensors for detection of pathogenic virus

Mokhtarzadeh

Eivazzadeh‐Keihan

Pashazadeh³

et al. 2017

TrAC Trends in Analytical Chemistry

255

146

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a b s t r a c tViruses are real menace to human safety that cause devastating viral disease. The high prevalence of these diseases is due to improper detecting tools. Therefore, there is a remarkable demand to identify viruses in a fast, selective and accurate way. Several biosensors have been designed and commercialized for detection of pathogenic viruses. However, they present many challenges. Nanotechnology overcomes these challenges and performs direct detection of molecular targets in real time. In this overview, studies concerning nanotechnology-based biosensors for pathogenic virus detection have been summarized, paying special attention to biosensors based on graphene oxide, silica, carbon nanotubes, gold, silver, zinc oxide and magnetic nanoparticles, which could pave the way to detect viral diseases and provide healthy life for infected patients.

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Detection of influenza virus by a biosensor based on the method combining electrochemiluminescence on binary SAMs modified Au electrode with an immunoliposome encapsulating Ru (II) complex

Cited by 24 publications

References 29 publications

Detection Methods of Human and Animal Influenza Virus—Current Trends

Detection Methods of Human and Animal Influenza Virus—Current Trends

Inorganic Complexes and Metal-Based Nanomaterials for Infectious Disease Diagnostics

Nanomaterial-based biosensors for detection of pathogenic virus

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