Detection of fraudulent vanillin labeled with carbon-13 in the carbonyl carbon

Forensic applications of isotope ratio mass spectrometry—A review

“…Numerous publications have addressed research in this field, and cover the analysis of substances such as flavours, fragrances, wine, fruit juice, honey, and vegetable oils [6,11,23,[52][53][54][55][56][57][58][59][60][61][62][63][64].…”

Obtenção de vanilina: oportunidade biotecnológica

“…Nesta análise é feito um perfil de isótopos usando um espectro de massa ( 13 C EMPI) ou o método de ressonância magné-tica nuclear ( 2 H-RMN) onde é possível destinguir a origem natural ou sintética da vanilina, já que a percentagem de 13 C na vanilina de origem da orquídea Vanilla planifolia difere da sintética [7][8][9][10][11][12][13] . Os métodos de análise usados para controle de qualidade incluem cinzas, acidez total, espectroscopia UV, cromatografia de camada delgada e em papel [14][15][16] , cromatografia gasosa e líquida de alta eficiência 17,18 .…”

Emerging techniques in vegetable oil analysis using stable isotope ratio mass spectrometry

“…Whilst, this technique is fully acknowledged as providing a practical tool for authenticity studies and a valuable insight into intra-molecular isotopic distributions, some limitations must be recognized in terms of sample quantities required, and measurement acquisition times. Position-specific isotope analysis (PSIA) measured by IRMS has been used previously in food authentication (Krueger and Krueger 1983;1985) but has not gained wide acceptance because the technique requires time consuming off-line chemical cleavage, and recovery of molecular fragments, without introducing isotopic fractionation. Nevertheless, IRMS does offer some advantages in terms of speed of instrumental analysis and the small quantities of sample required.…”