“…Simple, rapid tests have become available that enable testing at the point of client contact in outreach settings outside the laboratory, and an algorithm composed exclusively of tests that can be performed on site while the client waits would be highly desirable (6,14,15,24,38). Nucleic acid amplification tests (NAAT) have been used to identify primary HIV infection before seroconversion and may have an appropriate and useful role in screening and diagnostic algorithms (2,6,26,31,33,35,36,36,37,39,41). Because of all these developments and recognition that separate algorithms may be adequate for different purposes, we evaluated the performance of FDA-approved tests in the context of multiple diagnostic algorithms.…”