Detection and Isolation of Antiatherogenic and Antioxidant Substances Present in Olive Mill Wastes by a Novel Filtration System

Stamatakis, George; Tsantila, Nektaria; Samiotaki, Martina; Panayotou, George; Dimopoulos, Alexandros C.; Halvadakis, Constantinos P.; Demopoulos, Constantinos A.

doi:10.1021/jf9016288

Cited by 19 publications

(14 citation statements)

References 33 publications

(43 reference statements)

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“…was used for the preparation of the phenolic compounds extract (Supporting Information Section 1.2). The total phenolic content was determined in triplicate (Supporting Information Section 1.2).…”

Section: Methodsmentioning

confidence: 99%

High Resolution Mass Spectrometric Analysis of Secoiridoids and Metabolites as Biomarkers of Acute Olive Oil Intake—An Approach to Study Interindividual Variability in Humans

Silva

Garcia-Aloy

Figueira

et al. 2017

Molecular Nutrition Food Res

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Section: Methodsmentioning

confidence: 99%

High Resolution Mass Spectrometric Analysis of Secoiridoids and Metabolites as Biomarkers of Acute Olive Oil Intake—An Approach to Study Interindividual Variability in Humans

Silva

Garcia-Aloy

Figueira

et al. 2017

Molecular Nutrition Food Res

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“…For TPC measurement, the method described by Stamatakis et al (29) was applied, with some modifications. Briefly, the diluted sample extract (3•5 ml) was mixed to Folin-Ciocalteu's reagent (0•100 ml) and, after 3 min, 0•400 ml of sodium carbonate solution (35 %, w/v) was added to the mixture.…”

Section: Total Phenolic Content Of Raw and Cooked Common Beans Extractsmentioning

confidence: 99%

Human bioavailability of phenolic compounds found in common beans: the use of high-resolution MS to evaluate inter-individual variability

et al. 2019

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Although common beans (Phaseolus vulgaris L.) are consumed worldwide, studies on the metabolic fate of phenolic compounds from common beans are still very scarce. The present work aimed to study the bioavailability of phenolic compounds in human plasma and urine, after acute consumption of a single meal of cooked common beans. Blood and urine of seven volunteers were collected before (0 h) and at different time points (1, 2, 4, 6 and 8 h for plasma and 0–2, 2–4, 4–6, 6–8 and 8–24 h for urine) after beans’ intake. Ultra-high performance liquid chromatography-quadrupole-time of flight-MS (UPLC-Q-TOF-MS) was used for quantification. After beans’ intake, 405 (sd 3) g, containing 188 mg of phenolic compounds (expressed as gallic acid equivalents), there was a significant increase (P < 0·05) in the plasma concentration of six metabolites and in the urinary excretion of eleven metabolites. After 1 h post-consumption, metabolites, such as kaempferol-3-O-glucuronide, showed a significant increase in plasma concentration, suggesting kaempferol’s glucuronidation in the upper gastrointestinal tract. More than 50 % of the total amount of metabolites, such as 4-methylcatechol-O-sulphate and dihydrocaffeic acid-3-O-sulphate, were excreted after 8 h post-consumption, indicating colonic bacterial metabolism of the phenolic compounds. Partial least square-discriminant analysis models clearly showed clusters of metabolites, which contributed to extend the list of compounds related to cooked common beans’ human intake at different time points and showed the human inter-individual variability in plasma concentration as well as in urinary excreted metabolites, after cooked common beans’ intake.

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“…Folin'sreagent according to the method ofStamatakis [11]. The phenolic contents were expressed as mg of gallic acid equivalents per gram of dry weight (mg/g GAE DW).…”

Section: Determination Ofphenolic Chromatographic Profilementioning

confidence: 99%

Identification, Quantification and Antioxidant Activity of Hydro-alcoholic Extract of Artemisia campestris from Algeria

Bakchiche¹,

Gherib²,

Ghareeb³

et al. 2018

tjps

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In this study, the hydro-alcoholic extract of AlgerianArtemisia campestris was investigated for its phenolic constituents using HPLC-DAD-ESI-MS/MS. Also, the in vitro antioxidant activity and total phenolic content were evaluated via ORAC and Folin Ciocalteu assays, respectively. HPLC-DAD-ESI-MS/MS analysis revealed that the main tentatively identified compounds are caffeoylquinic acid isomers, flavonoids and benzoic acid derivatives. Additionally, the hydroalcoholic extract exhibited promising antioxidant activity value of 120.5 ± 10.4 μmol TEAC/gDW, and a strong correlation exists between thisactivity and the total phenolic contentvalue of 102.09 ± 1.65mg/g GAE DW. In conclusion, the hydroalcoholic extract of Artemisia campestrisis a promising candidate for the production of naturally occurring antioxidant agents.

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Detection and Isolation of Antiatherogenic and Antioxidant Substances Present in Olive Mill Wastes by a Novel Filtration System

Cited by 19 publications

References 33 publications

High Resolution Mass Spectrometric Analysis of Secoiridoids and Metabolites as Biomarkers of Acute Olive Oil Intake—An Approach to Study Interindividual Variability in Humans

High Resolution Mass Spectrometric Analysis of Secoiridoids and Metabolites as Biomarkers of Acute Olive Oil Intake—An Approach to Study Interindividual Variability in Humans

Human bioavailability of phenolic compounds found in common beans: the use of high-resolution MS to evaluate inter-individual variability

Identification, Quantification and Antioxidant Activity of Hydro-alcoholic Extract of Artemisia campestris from Algeria

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