Detection and estimation of isopropyl methylphosphonofluoridate and O-ethyl S-diisopropylaminoethylmethylphosphonothioate in sea water in parts-per-trillion level

Michel, Harry O.; Gordon, Eric C.; Epstein, Joseph A.

doi:10.1021/es60083a010

Cited by 38 publications

(12 citation statements)

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“…Analysis of OPs in environmental and biological samples is routinely conducted using various analytical techniques, including nuclear magnetic resonance (NMR) spectroscopy [ 21 ], gas, liquid or thin layer chromatography, and mass spectrometry [ 20 ]. A variety of approaches have been investigated for sensors, including enzymatic assays [ 18 ], molecular imprinting coupled with luminescence (using lanthanides) [ 14 – 17 ], colorimetric methods [ 22 – 24 ], surface acoustic waves [ 25 , 26 ], fluorescent organic molecules [ 27 – 29 ], and interferometry [ 19 ]. The most common ways for detecting OP pesticides are chromatographic methods coupled with different detectors and different types of spectroscopy, immunoassays, and enzyme biosensors based on inhibition of cholinesterase activity [ 30 – 32 ].…”

Section: Advances In Detection Of Op Compoundsmentioning

confidence: 99%

Fluorescent Chemosensors for Toxic Organophosphorus Pesticides: A Review

Obare

Guo

et al. 2010

Sensors

131

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Many organophosphorus (OP) based compounds are highly toxic and powerful inhibitors of cholinesterases that generate serious environmental and human health concerns. Organothiophosphates with a thiophosphoryl (P=S) functional group constitute a broad class of these widely used pesticides. They are related to the more reactive phosphoryl (P=O) organophosphates, which include very lethal nerve agents and chemical warfare agents, such as, VX, Soman and Sarin. Unfortunately, widespread and frequent commercial use of OP-based compounds in agricultural lands has resulted in their presence as residues in crops, livestock, and poultry products and also led to their migration into aquifers. Thus, the design of new sensors with improved analyte selectivity and sensitivity is of paramount importance in this area. Herein, we review recent advances in the development of fluorescent chemosensors for toxic OP pesticides and related compounds. We also discuss challenges and progress towards the design of future chemosensors with dual modes for signal transduction.

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Section: Advances In Detection Of Op Compoundsmentioning

confidence: 99%

Fluorescent Chemosensors for Toxic Organophosphorus Pesticides: A Review

Obare

Guo

et al. 2010

Sensors

131

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“…There have been many innovations for the detection of this species including colorimetric detection methods [7,8] surface acoustic wave devices [9,10], enzymatic assays [11], interferometry [12] and fluorescent sensors [13][14][15]. However, all are plagued by at least one limitation or other such as slow response, lack of selectivity, poor sensitivity, operational complexities or non-portability.…”

Section: Introductionmentioning

confidence: 99%

Imprinted Polymer Inclusion Membrane Based Potentiometric Sensor for Determination and Quantification of Diethyl Chlorophosphate in Natural Waters

Vishnuvardhan¹,

Yakkala²,

Prathish³

et al. 2011

AJAC

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Biomimetic potentiometric sensor for the determination of diethyl chlorophosphate was developed using imprinted polymer inclusion membrane strategy. Semi-covalent imprinted and non-imprinted polymer particles were synthesized and found that non-imprinted polymer inclusion membrane was unstable in contrast to imprinted polymer inclusion membrane in determination and quantification of diethyl chlorophosphate. Imprinted polymer inclusion membrane based sensor found to be pH dependant with a 5 min equilibrium response time at pH = 10.5 and linearly responds to diethyl chlorophosphate in the concentration range of 1 × 10 -9 to 1 × 10 -4 and 1 × 10 -4 to 1 × 10 -2 mol·L -1 with a detection limit of 1 × 10 -9 mol·L -1 (0.17 ppb). It was found that diethyl chlorophosphate response was selective against various selected interferents like pinacolyl methylphosphonate, dimethyl methyl phosphonate, methylphosphonic acid, Phorate and 2, 4-D. The developed sensor was found to be stable for 3 months and can be reusable more than 30 times without loosing sensitivity. The developed sensor was successfully applied for the determination of diethyl chlorophosphate in natural waters.

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“…This detection, when integrated with decontamination, can be confidence boosting and user-friendly. Additionally there have been many other methods developed for the detection of these species, including colourimetry 24 , surface acoustic wave devices (SAW) [25][26] , enzymatic assays [27][28] , and interferometry [29][30] , however, presently these are not suitable for integration with the decontamination systems 31 . Besides this, nanosized particles of MgO, Al 2 O 3 and CaO are promising reactive sorbent materials that have been used as advanced decontaminant materials.…”

Section: Introductionmentioning

confidence: 99%

Decontamination of Chemical Warfare Agents

Singh

Prasad

Pandey

et al. 2010

DSJ

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Chemical warfare agents (CWA) pose inevitable threat, both to soldiers and civilians. Risk on contact with these deadly agents can be avoided by neutralisation of their toxic effects. A suitable media with essential physico-chemical properties is required for this purpose. Considerable efforts have been made to develop several decontamination media suitable for neutralisation of highly toxic CWAs. This paper reviews history and details of recent technological advancements in the development of versatile, broad spectrum decontamination formulations against CWAs, as also nanosized metal oxides as CWA decontaminants.

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Detection and estimation of isopropyl methylphosphonofluoridate and O-ethyl S-diisopropylaminoethylmethylphosphonothioate in sea water in parts-per-trillion level

Abstract: The milk portion of the diet had 0.16-0.46 mg Sr, with an average of 0.29 mg, or 32.1% (Rehnberg et al., 1969). In the present study, analyses of the diets of children showed intakes of 0.792-2.43 mg Sr, with an average of 1.237

Cited by 38 publications

References 1 publication

Fluorescent Chemosensors for Toxic Organophosphorus Pesticides: A Review

Fluorescent Chemosensors for Toxic Organophosphorus Pesticides: A Review

Imprinted Polymer Inclusion Membrane Based Potentiometric Sensor for Determination and Quantification of Diethyl Chlorophosphate in Natural Waters

Decontamination of Chemical Warfare Agents

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