This paper presents model based approach for diagnosis of open circuit power switch faults in full bridge DC-DC converter of a photovoltaic system. The control circuitry of the proposed converter monitors and regulates output current, whenever output current lowers, controller monitors current at test points and localizes faulty switch by comparing fault features. This minimizes efforts required for manual diagnosis of faulty switch. The faults will be detected and diagnosed automatically and displayed on LCD display. In this a model of DC-DC converter is prepared and simulated in SimPowerSystems toolset of MATLAB/Simulink and obtained results are presented.