Design of a Minimal System for Self-replication of Rectangular Patterns of DNA Tiles

Gautam, Vinay Kumar; Czeizler, Eugen; Haddow, Pauline C.; Kuiper, Martin

doi:10.1007/978-3-319-13749-0_11

Cited by 2 publications

(2 citation statements)

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“…This section describes the design of Tile Pattern Self-replication Simulator (TPSS) based on its previously proposed theoretical model [5].…”

Section: Tile Pattern Self-replication Simulatormentioning

confidence: 99%

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Simulating Self-replicating Patterns of DNA Tiles

Gautam¹,

Prasath²

2017

Proceedings of the 10th EAI International Conference on Bio-Inspired Information and Communications Technologies (Formerly BION

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This paper presents a simulation framework in which a pre-assembled rectangular pattern of DNA tiles can be put together with sets of other DNA tiles to autonomously assemble replicas of itself in a discrete two-dimensional grid.The simulator implements both abstract and chemical kinetics based modelling to simulate the tile pattern self-replication. While the abstract model uses only logical matching between the edges of tiles to guide the assembly process, the chemical kinetics model calculates stochastic preference for attachment and/or detachment of each tile during the self-replication. A comparison is made between pattern self-replication timing in the abstract model and cellular automata based models. Simulation of chemical kinetics behaviour shows that the physico-chemical parameters of tile self-assembly govern the tractability of self-replication process and reliability of replicating patterns. Observations are made about the limitations of the simulator, and a few suggestions for improvement and further studies are discussed.

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“…This section describes the design of Tile Pattern Self-replication Simulator (TPSS) based on its previously proposed theoretical model [5].…”

Section: Tile Pattern Self-replication Simulatormentioning

confidence: 99%

“…In this paper, we describe a simulation framework for minimal system of self-replicating patterns of DNA tiles, earlier studied in Gautam et al [5].…”

Section: Introductionmentioning

confidence: 99%