Design and synthesis of dual-excitation fluorescent probe, Tb3+-dtpa-bis(fluorescein), and application in detection of hydrazine in environmental water samples and live cells

Yu, Zhiyue; Li, Na; Jia, Haishuang; Hao, Wei; Wang, Jun; Song, Youtao

doi:10.1016/j.dyepig.2018.10.044

Cited by 8 publications

(1 citation statement)

References 54 publications

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“…As reported, a typical probe includes the fluorophore (such as benzothiazole [ 14 ], 1,8-naphthalene imide [ 15 ], coumarin [ 16 ], rhodamine [ 17 ], phenothiazine [ 18 ], carbazole [ 19 ], and cyanine dye [ 20 ]) and the recognition group (such as acetyl [ 21 ], levulinate [ 22 ], 4-bromo butyrate [ 23 ], phthalimide [ 24 ], aldehyde [ 25 ], cyano [ 26 ]). As we claimed in our previous work [ 27 ], compared with complex tools (such as rare earth [ 28 ], aggregation-induced enhancement (AIE) [ 29 ], nanoparticles [ 30 ], or carbon dots [ 31 ]), small molecular probes were preferred in the closed-loop monitoring of hydrazine circulation. Thus, novel mechanisms for recognizing hydrazine with specific cases are still urgently needed.…”

Section: Introductionmentioning

confidence: 99%

A Novel Fluorescent Probe for Selective Detection of Hydrazine and Its Application in Imaging

Man

Yang

et al. 2021

Biosensors

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In this work, a novel fluorescent probe with first-time-selected thiazepine backbone, TZPzine-1, was developed for selective detection of hydrazine in water samples and living cells. Chosen from our recent anti-cancer agents, TZPzine-1 inferred structurally based advantages of the optical adjustability and the hydrazine-trapping approach. It also showed applicable properties including high sensitivity (LOD = 50 nM), wide linear range (0–15 equiv.), high selectivity (especially from competing species), rapid response (within 20 min), and practical steadiness in various pH (6.0–11.0) and temperature (15–50 °C) conditions. To satisfy the interdisciplinary requirements in environmental toxicology, TZPzine-1 was successfully applied in water samples and living cells. We hope that the information in this work, as well as the concept of monitoring the nitrogen cycle, may be referable for future research on systematic management.

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