Design and fabrication of a silica on silicon integrated optical biochip as a fluorescence microarray platform

Application of microfluidic chip with integrated optics for electrophoretic separations of proteins☆

“…To overcome these limitations, various concepts of the integration of optical detection systems have been proposed [7][8][9][10][11][12][13][14][15][16][17][18][19]. In our previous paper [20] we described in details the fabrication method and the basic optical characteristics of a microsystem, featuring integrated microfluidic and optical detection system.…”

A novel concept of the integrated fluorescence detection system and its application in a lab-on-a-chip microdevice

“…Microchips containing optical fibres, planar waveguides, or spin-on-glass waveguides [7][8][9][10][11][12][13][14][15][16][17][18], integrated with their microfluidic structure, have been built. In this paper, a different concept of integration is proposed.…”

Recent developments in detection for microfluidic systems

“…There were, however, problems with detection of stray light for that particular chip design. Doped SiO 2 waveguides were also used in the device by Ruano and coworkers [61], where a 1:16 waveguide beam splitter was integrated for parallel probing of an array of 16 microchambers. The chip was, further, designed so that fluorescence and absorbance in principle could be detected simultaneously.…”